Commentary: Can FXR serve as a potential target for COVID-19 prevention?

Commentary: Can FXR serve as a potential target for COVID-19 prevention?

Bibliographic Details
Main Authors:	Juan Pang, Jia Nuo Feng, Wenhua Ling, Tianru Jin
Format:	Article
Language:	English
Published:	Elsevier 2023-04-01
Series:	Acta Pharmaceutica Sinica B
Subjects:	COVID-19 ACE2 FXR Bile acid
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211383523000254

Similar Items

Alterations in the gut microbiota and serum metabolomics of spontaneous cholestasis caused by loss of FXR signal in mice
by: Shizhang Wei, et al.
Published: (2023-05-01)

Effects of cholesterol-lowering probiotics on non-alcoholic fatty liver disease in FXR gene knockout mice
by: Minghua Yang, et al.
Published: (2023-07-01)

Dietary bile acids improve breast muscle growth in chickens through FXR/IGF2 pathway
by: Liang Chen, et al.
Published: (2024-02-01)

Dietary Resistant Starch Regulates Bile Acid Metabolism by Modulating the FXR/LRH-1 Signaling Pathway in Broilers
by: Zhenxin Wang, et al.
Published: (2023-11-01)

Triclosan exposure causes abnormal bile acid metabolism through IL-1β-NF-κB-Fxr signaling pathway
by: Jing Liu, et al.
Published: (2024-10-01)

Small intestinal taurochenodeoxycholic acid-FXR axis alters local nutrient-sensing glucoregulatory pathways in rats
by: T.M. Zaved Waise, et al.
Published: (2021-02-01)

Non-steroidal FXR agonist cilofexor improves cholestatic liver injury in the Mdr2-/- mouse model of sclerosing cholangitis
by: Claudia D. Fuchs, et al.
Published: (2023-11-01)

Isorhamnetin in Quinoa Whole-Grain Flavonoids Intervenes in Non-Alcoholic Fatty Liver Disease by Modulating Bile Acid Metabolism through Regulation of FXR Expression
by: Xiaoqin La, et al.
Published: (2024-09-01)

Effects of Intestinal FXR-Related Molecules on Intestinal Mucosal Barriers in Biliary Tract Obstruction
by: Meng Yan, et al.
Published: (2022-06-01)

Bile Acid Physiology
by: Agostino Di Ciaula, et al.
Published: (2017-11-01)

Suppressing FXR promotes antiviral effects of bile acids via enhancing the interferon transcription
by: Xue Liang, et al.
Published: (2024-08-01)

Gypensapogenin A-Liposomes Efficiently Ameliorates Hepatocellular Lipid Accumulation via Activation of FXR Receptor
by: Yidan Deng, et al.
Published: (2024-08-01)

Depletion of gut microbiota induces skeletal muscle atrophy by FXR-FGF15/19 signalling
by: Yixuan Qiu, et al.
Published: (2021-01-01)

FXR Signaling-Mediated Bile Acid Metabolism Is Critical for Alleviation of Cholesterol Gallstones by Lactobacillus Strains
by: Xin Ye, et al.
Published: (2022-10-01)

HuangQi ChiFeng decoction maintains gut microbiota and bile acid homeostasis through FXR signaling to improve atherosclerosis
by: Jiaqi Fu, et al.
Published: (2023-11-01)

Pulsatilla decoction alleviates DSS-induced UC by activating FXR-ASBT pathways to ameliorate disordered bile acids homeostasis
by: Ying Xiao, et al.
Published: (2024-06-01)

Profile of the bile acid FXR-FGF15 pathway in the glucolipid metabolism disorder of diabetic mice suffering from chronic stress
by: Weijia Cai, et al.
Published: (2023-11-01)

Ginsenoside Rh4 Improves Hepatic Lipid Metabolism and Inflammation in a Model of NAFLD by Targeting the Gut Liver Axis and Modulating the FXR Signaling Pathway
by: Siming Yang, et al.
Published: (2023-06-01)

Tailoring FXR Modulators for Intestinal Specificity: Recent Progress and Insights
by: Amanda Morrison, et al.
Published: (2024-04-01)

Genes and pathways differentially expressed in the brains of Fxr2 knockout mice
by: Sebastiano Cavallaro, et al.
Published: (2008-12-01)

Targeting Farnesoid X receptor (FXR) for developing novel therapeutics against cancer
by: Sosmitha Girisa, et al.
Published: (2021-07-01)

Hepatic Bile Acid Reuptake in the Rat Depends on Bile Acid Conjugation but Not on Agonistic Properties towards FXR and TGR5
by: Samuel A. J. Trammell, et al.
Published: (2020-05-01)

Regulation of cholesterol-7α-hydroxylase: BAREly missing a SHP
by: Roger A. Davis, et al.
Published: (2002-04-01)

Gut microbiota-bile acid crosstalk regulates murine lipid metabolism via the intestinal FXR-FGF19 axis in diet-induced humanized dyslipidemia
by: Hongtao Xu, et al.
Published: (2023-11-01)

Notoginsenoside Ft1 acts as a TGR5 agonist but FXR antagonist to alleviate high fat diet-induced obesity and insulin resistance in mice
by: Lili Ding, et al.
Published: (2021-06-01)

Berberine Alleviates Non-alcoholic Steatohepatitis Through Modulating Gut Microbiota Mediated Intestinal FXR Activation
by: Xiangbing Shu, et al.
Published: (2021-09-01)

Bacteroides fragilis alleviates necrotizing enterocolitis through restoring bile acid metabolism balance using bile salt hydrolase and inhibiting FXR-NLRP3 signaling pathway
by: Zhenhui Chen, et al.
Published: (2024-12-01)

Functional changes of the gastric bypass microbiota reactivate thermogenic adipose tissue and systemic glucose control via intestinal FXR-TGR5 crosstalk in diet-induced obesity
by: Julia Münzker, et al.
Published: (2022-06-01)

Hammerhead-type FXR agonists induce an enhancer RNA Fincor that ameliorates nonalcoholic steatohepatitis in mice
by: Jinjing Chen, et al.
Published: (2024-04-01)

SIRT1 activation synergizes with FXR agonism in hepatoprotection via governing nucleocytoplasmic shuttling and degradation of FXR
by: Shuang Cui, et al.
Published: (2023-02-01)

Comparative Behavioral Phenotypes of Fmr1 KO, Fxr2 Het, and Fmr1 KO/Fxr2 Het Mice
by: Rachel Michelle Saré, et al.
Published: (2019-01-01)

Emodin alleviates cholestatic liver injury by modulating Sirt1/Fxr signaling pathways
by: Zhi Hu, et al.
Published: (2024-07-01)

FXR activation promotes intestinal cholesterol excretion and attenuates hyperlipidemia in SR‐B1‐deficient mice fed a high‐fat and high‐cholesterol diet
by: Amar B. Singh, et al.
Published: (2020-03-01)

Hyodeoxycholic acid inhibits colorectal cancer proliferation through the FXR/EREG/EGFR axis
by: Qiang Pang, et al.
Published: (2025-01-01)

Bioenergetic cues shift FXR splicing towards FXRα2 to modulate hepatic lipolysis and fatty acid metabolism
by: Jorge C. Correia, et al.
Published: (2015-12-01)

Evidence for the involvement of FXR signaling in ovarian granulosa cell function
by: Kentaro TAKAE, et al.
Published: (2018-11-01)

Activation of FXR pathway does not alter glial cell function
by: Stefanie Albrecht, et al.
Published: (2017-03-01)

Ablation of liver Fxr results in an increased colonic mucus barrier in mice
by: Noortje Ijssennagger, et al.
Published: (2021-10-01)

Bile Acids Induce Neurite Outgrowth in Nsc-34 Cells via TGR5 and a Distinct Transcriptional Profile
by: Hayley D. Ackerman, et al.
Published: (2023-01-01)

Dietary acetic acid suppress high-fat diet-induced obesity in mice by altering taurine conjugated bile acids metabolism
by: Rui Wang, et al.
Published: (2022-01-01)