Probing the Anti-Cancer Potency of Sulfated Galactans on Cholangiocarcinoma Cells Using Synchrotron FTIR Microspectroscopy, Molecular Docking, and In Vitro Studies

Probing the Anti-Cancer Potency of Sulfated Galactans on Cholangiocarcinoma Cells Using Synchrotron FTIR Microspectroscopy, Molecular Docking, and In Vitro Studies

Sulfated galactans (SG) isolated from red alga <i>Gracilaria fisheri</i> have been reported to inhibit the growth of cholangiocarcinoma (CCA) cells, which was similar to the epidermal growth factor receptor (EGFR)-targeted drug, cetuximab. Herein, we studied the anti-cancer potency of SG...

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Bibliographic Details
Main Authors: Boonyakorn Boonsri, Kiattawee Choowongkomon, Buabarn Kuaprasert, Thanvarin Thitiphatphuvanon, Kittiya Supradit, Apinya Sayinta, Jinchutha Duangdara, Tawut Rudtanatip, Kanokpan Wongprasert
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Marine Drugs
Subjects:
red alga <i>Gracilaria fisheri</i>
sulfated galactans
synchrotron-FTIR-MS
molecular docking
epidermal growth factor receptor
anti-cancer
Online Access:https://www.mdpi.com/1660-3397/19/5/258

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