Investigation of MRP1 and ABCG2 Gene Expression in Chronic Myeloid Leukemia (CML) Patients

Investigation of MRP1 and ABCG2 Gene Expression in Chronic Myeloid Leukemia (CML) Patients

Background: This study evaluated and compared the quantitative expression of Multidrug Resistance-associated Protein 1 (MRP1) and ATP Binding Cassette subfamily G member 2 ( ABCG2), two Multidrug Resistance (MDR) related genes, in 30 CML patients and 27 normal subjects. Methods: Total RNA was ext...

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Bibliographic Details
Main Authors: Saeed Solali, Masoumeh Fardi, Shohreh Almasi, Mohammad Reza Aliparasti
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2020-12-01
Series:Basic & Clinical Cancer Research
Subjects:
ABCG2
MRP1
CML
Imatinib
Gene expression
Online Access:https://bccr.tums.ac.ir/index.php/bccrj/article/view/358

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