Short QT interval syndrome
Every year, sudden cardiac death (SCD) takes lives of 400 000 American citizens, and in 10-20% ofthe cases, fatal outcome is explained by hereditary pathology. Short QT interval syndrome remains rarely diagnosed, and virtually unknown, as it was described just recently. Its clinical course is charac...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
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«SILICEA-POLIGRAF» LLC
1970-01-01
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| Series: | Кардиоваскулярная терапия и профилактика |
| Subjects: | |
| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/1590 |
| _version_ | 1827064187296153600 |
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| author | I. G. Fomina A. I. Tarzimanova A. V. Vetluzhsky |
| author_facet | I. G. Fomina A. I. Tarzimanova A. V. Vetluzhsky |
| author_sort | I. G. Fomina |
| collection | DOAJ |
| description | Every year, sudden cardiac death (SCD) takes lives of 400 000 American citizens, and in 10-20% ofthe cases, fatal outcome is explained by hereditary pathology. Short QT interval syndrome remains rarely diagnosed, and virtually unknown, as it was described just recently. Its clinical course is characterized by syncope or fainting episodes, and SCD in patients with corrected QT interval <320 ms. In patients with short QT syndrome, syncope can be caused by atrial fibrillation (AF) paroxysms or ventricular arrhythmias. AF episodes are typically the first manifestation ofthe disease, being registered more often in children and adolescents; some cases in new-born babies have been described. According to genetic examination results, short QT syndrome is a hereditary pathology, explained by various mutations of potassium channel gene. Genetic polymorphism in short QT syndrome manifests during antiarrhythmic treatment. At present, the single effective therapeutic method for such patients is cardioverter-defibrillator implantation. |
| first_indexed | 2024-04-10T03:42:00Z |
| format | Article |
| id | doaj.art-b21a4543077d4def93f12a23065cba55 |
| institution | Directory Open Access Journal |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| last_indexed | 2025-03-19T22:43:09Z |
| publishDate | 1970-01-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj.art-b21a4543077d4def93f12a23065cba552024-10-17T12:21:20Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01251970-01-015783851307Short QT interval syndromeI. G. Fomina0A. I. Tarzimanova1A. V. Vetluzhsky2I.M. Sechenov Moscow Medical Academy. MoscowI.M. Sechenov Moscow Medical Academy. MoscowI.M. Sechenov Moscow Medical Academy. MoscowEvery year, sudden cardiac death (SCD) takes lives of 400 000 American citizens, and in 10-20% ofthe cases, fatal outcome is explained by hereditary pathology. Short QT interval syndrome remains rarely diagnosed, and virtually unknown, as it was described just recently. Its clinical course is characterized by syncope or fainting episodes, and SCD in patients with corrected QT interval <320 ms. In patients with short QT syndrome, syncope can be caused by atrial fibrillation (AF) paroxysms or ventricular arrhythmias. AF episodes are typically the first manifestation ofthe disease, being registered more often in children and adolescents; some cases in new-born babies have been described. According to genetic examination results, short QT syndrome is a hereditary pathology, explained by various mutations of potassium channel gene. Genetic polymorphism in short QT syndrome manifests during antiarrhythmic treatment. At present, the single effective therapeutic method for such patients is cardioverter-defibrillator implantation.https://cardiovascular.elpub.ru/jour/article/view/1590sudden deathshort qt interval syndromecardioverter-defibrillator implantation |
| spellingShingle | I. G. Fomina A. I. Tarzimanova A. V. Vetluzhsky Short QT interval syndrome Кардиоваскулярная терапия и профилактика sudden death short qt interval syndrome cardioverter-defibrillator implantation |
| title | Short QT interval syndrome |
| title_full | Short QT interval syndrome |
| title_fullStr | Short QT interval syndrome |
| title_full_unstemmed | Short QT interval syndrome |
| title_short | Short QT interval syndrome |
| title_sort | short qt interval syndrome |
| topic | sudden death short qt interval syndrome cardioverter-defibrillator implantation |
| url | https://cardiovascular.elpub.ru/jour/article/view/1590 |
| work_keys_str_mv | AT igfomina shortqtintervalsyndrome AT aitarzimanova shortqtintervalsyndrome AT avvetluzhsky shortqtintervalsyndrome |