X4 tropic multi-drug resistant quasi-species detected at the time of primary HIV-1 infection remain exclusive or at least dominant far from PHI.

X4 tropic multi-drug resistant quasi-species detected at the time of primary HIV-1 infection remain exclusive or at least dominant far from PHI.

Our objective was to analyze the evolution of resistance mutations (RM) and viral tropism of multi-drug-resistant (MDR) strains detected at primary HIV-1 infection (PHI). MDR HIV strain was defined as the presence of genotypic resistance to at least 1 antiretroviral of the 3 classes. Tropism determi...

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Bibliographic Details
Main Authors: Jade Ghosn, Julie Galimand, Stéphanie Raymond, Laurence Meyer, Christiane Deveau, Cécile Goujard, Jacques Izopet, Christine Rouzioux, Marie-Laure Chaix, ANRS CO 06 PRIMO cohort
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3160852?pdf=render

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