Synchronous Occurrence of Advanced Neuroendocrine Carcinoma and Tubular Adenocarcinoma of the Rectum
This report presents a rare case with the synchronous occurrence of advanced neuroendocrine carcinoma (NEC) and tubular adenocarcinoma of the rectum. A 52-year-old Japanese male presented with general fatigue and bloody stool. Endoscopic examination showed an ulcerated lesion of the lower rectum. Th...
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| Format: | Article |
| Language: | English |
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Karger Publishers
2013-03-01
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| Series: | Case Reports in Gastroenterology |
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| Online Access: | http://www.karger.com/Article/FullText/350252 |
| _version_ | 1819019875703586816 |
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| author | Yoshifumi Nakayama Takayuki Torigoe Noritaka Minagawa Toshihito Uehara Koji Yamaguchi |
| author_facet | Yoshifumi Nakayama Takayuki Torigoe Noritaka Minagawa Toshihito Uehara Koji Yamaguchi |
| author_sort | Yoshifumi Nakayama |
| collection | DOAJ |
| description | This report presents a rare case with the synchronous occurrence of advanced neuroendocrine carcinoma (NEC) and tubular adenocarcinoma of the rectum. A 52-year-old Japanese male presented with general fatigue and bloody stool. Endoscopic examination showed an ulcerated lesion of the lower rectum. The pathological diagnosis of biopsy specimens from this lesion indicated moderately differentiated adenocarcinoma. He was referred to the surgical outpatient clinic with advanced rectal cancer. Barium enema indicated two lesions in the upper and lower rectum. Computed tomography revealed multiple hepatic metastases. A low anterior resection was performed with lymph node dissection. The resected specimen indicated an elevated lesion with ulceration in the upper rectum and an ulcerated lesion in the lower rectum. Histopathological and immunohistochemical analyses revealed NEC from the upper rectum and moderately differentiated tubular adenocarcinoma from the lower rectum. These two lesions were completely separated from each other. Therefore, this case demonstrates the synchronous occurrence of advanced NEC and tubular adenocarcinoma in the rectum. |
| first_indexed | 2024-12-21T03:42:16Z |
| format | Article |
| id | doaj.art-b21f855b55ce46f0983736124553f8f4 |
| institution | Directory Open Access Journal |
| issn | 1662-0631 |
| language | English |
| last_indexed | 2024-12-21T03:42:16Z |
| publishDate | 2013-03-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Gastroenterology |
| spelling | doaj.art-b21f855b55ce46f0983736124553f8f42022-12-21T19:17:11ZengKarger PublishersCase Reports in Gastroenterology1662-06312013-03-017111712110.1159/000350252350252Synchronous Occurrence of Advanced Neuroendocrine Carcinoma and Tubular Adenocarcinoma of the RectumYoshifumi NakayamaTakayuki TorigoeNoritaka MinagawaToshihito UeharaKoji YamaguchiThis report presents a rare case with the synchronous occurrence of advanced neuroendocrine carcinoma (NEC) and tubular adenocarcinoma of the rectum. A 52-year-old Japanese male presented with general fatigue and bloody stool. Endoscopic examination showed an ulcerated lesion of the lower rectum. The pathological diagnosis of biopsy specimens from this lesion indicated moderately differentiated adenocarcinoma. He was referred to the surgical outpatient clinic with advanced rectal cancer. Barium enema indicated two lesions in the upper and lower rectum. Computed tomography revealed multiple hepatic metastases. A low anterior resection was performed with lymph node dissection. The resected specimen indicated an elevated lesion with ulceration in the upper rectum and an ulcerated lesion in the lower rectum. Histopathological and immunohistochemical analyses revealed NEC from the upper rectum and moderately differentiated tubular adenocarcinoma from the lower rectum. These two lesions were completely separated from each other. Therefore, this case demonstrates the synchronous occurrence of advanced NEC and tubular adenocarcinoma in the rectum.http://www.karger.com/Article/FullText/350252Neuroendocrine carcinomaSmall cell typeTubular adenocarcinomaSynchronous occurrenceRectum |
| spellingShingle | Yoshifumi Nakayama Takayuki Torigoe Noritaka Minagawa Toshihito Uehara Koji Yamaguchi Synchronous Occurrence of Advanced Neuroendocrine Carcinoma and Tubular Adenocarcinoma of the Rectum Case Reports in Gastroenterology Neuroendocrine carcinoma Small cell type Tubular adenocarcinoma Synchronous occurrence Rectum |
| title | Synchronous Occurrence of Advanced Neuroendocrine Carcinoma and Tubular Adenocarcinoma of the Rectum |
| title_full | Synchronous Occurrence of Advanced Neuroendocrine Carcinoma and Tubular Adenocarcinoma of the Rectum |
| title_fullStr | Synchronous Occurrence of Advanced Neuroendocrine Carcinoma and Tubular Adenocarcinoma of the Rectum |
| title_full_unstemmed | Synchronous Occurrence of Advanced Neuroendocrine Carcinoma and Tubular Adenocarcinoma of the Rectum |
| title_short | Synchronous Occurrence of Advanced Neuroendocrine Carcinoma and Tubular Adenocarcinoma of the Rectum |
| title_sort | synchronous occurrence of advanced neuroendocrine carcinoma and tubular adenocarcinoma of the rectum |
| topic | Neuroendocrine carcinoma Small cell type Tubular adenocarcinoma Synchronous occurrence Rectum |
| url | http://www.karger.com/Article/FullText/350252 |
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