DLC-Coated Ferroelectric Membranes as Vascular Patches: Physico-Chemical Properties and Biocompatibility

In this paper, the results on the fabrication of ferroelectric membranes as vascular patches with modified surfaces are presented. For the modification of a membrane surface contacting blood, DLC coating was deposited using the pulsed vacuum arc deposition technique. The physico-chemical properties...

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Main Authors: Yuri Yuriev, Semen Goreninskii, Artem Runts, Elisaveta Prosetskaya, Evgenii Plotnikov, Darya Shishkova, Yulia Kudryavtseva, Evgeny Bolbasov
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Membranes
Subjects:
Online Access:https://www.mdpi.com/2077-0375/11/9/690
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author Yuri Yuriev
Semen Goreninskii
Artem Runts
Elisaveta Prosetskaya
Evgenii Plotnikov
Darya Shishkova
Yulia Kudryavtseva
Evgeny Bolbasov
author_facet Yuri Yuriev
Semen Goreninskii
Artem Runts
Elisaveta Prosetskaya
Evgenii Plotnikov
Darya Shishkova
Yulia Kudryavtseva
Evgeny Bolbasov
author_sort Yuri Yuriev
collection DOAJ
description In this paper, the results on the fabrication of ferroelectric membranes as vascular patches with modified surfaces are presented. For the modification of a membrane surface contacting blood, DLC coating was deposited using the pulsed vacuum arc deposition technique. The physico-chemical properties and cytotoxicity of the membranes modified under various conditions were studied. It was found that DLC coatings do not affect membrane microstructure, preserving its crystal structure as well as its high strength and elongation. It was revealed that an increase in the capacitor storage voltage results in the rise in sp<sup>2</sup>- and sp-hybridized carbon concentration, which makes it possible to control the chemical structure and surface energy of the modified surface. The experiments with 3T3L1 fibroblasts showed no toxic effects of the materials extracts.
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spelling doaj.art-b220ddbb19b94d14ba503068d7b6c21a2023-11-22T14:10:28ZengMDPI AGMembranes2077-03752021-09-0111969010.3390/membranes11090690DLC-Coated Ferroelectric Membranes as Vascular Patches: Physico-Chemical Properties and BiocompatibilityYuri Yuriev0Semen Goreninskii1Artem Runts2Elisaveta Prosetskaya3Evgenii Plotnikov4Darya Shishkova5Yulia Kudryavtseva6Evgeny Bolbasov7B.P. Veinberg Research and Educational Centre, Tomsk Polytechnic University, 634050 Tomsk, RussiaN.M. Kizhner Research and Educational Centre, Tomsk Polytechnic University, 634050 Tomsk, RussiaB.P. Veinberg Research and Educational Centre, Tomsk Polytechnic University, 634050 Tomsk, RussiaB.P. Veinberg Research and Educational Centre, Tomsk Polytechnic University, 634050 Tomsk, RussiaResearch School of Chemistry & Applied Biomedical Sciences, Tomsk Polytechnic University, 634050 Tomsk, RussiaResearch Institute for Complex Issues of Cardiovascular Diseases, 650002 Kemerovo, RussiaResearch Institute for Complex Issues of Cardiovascular Diseases, 650002 Kemerovo, RussiaB.P. Veinberg Research and Educational Centre, Tomsk Polytechnic University, 634050 Tomsk, RussiaIn this paper, the results on the fabrication of ferroelectric membranes as vascular patches with modified surfaces are presented. For the modification of a membrane surface contacting blood, DLC coating was deposited using the pulsed vacuum arc deposition technique. The physico-chemical properties and cytotoxicity of the membranes modified under various conditions were studied. It was found that DLC coatings do not affect membrane microstructure, preserving its crystal structure as well as its high strength and elongation. It was revealed that an increase in the capacitor storage voltage results in the rise in sp<sup>2</sup>- and sp-hybridized carbon concentration, which makes it possible to control the chemical structure and surface energy of the modified surface. The experiments with 3T3L1 fibroblasts showed no toxic effects of the materials extracts.https://www.mdpi.com/2077-0375/11/9/690ferroelectric membranesDLC coatingsvascular patches
spellingShingle Yuri Yuriev
Semen Goreninskii
Artem Runts
Elisaveta Prosetskaya
Evgenii Plotnikov
Darya Shishkova
Yulia Kudryavtseva
Evgeny Bolbasov
DLC-Coated Ferroelectric Membranes as Vascular Patches: Physico-Chemical Properties and Biocompatibility
Membranes
ferroelectric membranes
DLC coatings
vascular patches
title DLC-Coated Ferroelectric Membranes as Vascular Patches: Physico-Chemical Properties and Biocompatibility
title_full DLC-Coated Ferroelectric Membranes as Vascular Patches: Physico-Chemical Properties and Biocompatibility
title_fullStr DLC-Coated Ferroelectric Membranes as Vascular Patches: Physico-Chemical Properties and Biocompatibility
title_full_unstemmed DLC-Coated Ferroelectric Membranes as Vascular Patches: Physico-Chemical Properties and Biocompatibility
title_short DLC-Coated Ferroelectric Membranes as Vascular Patches: Physico-Chemical Properties and Biocompatibility
title_sort dlc coated ferroelectric membranes as vascular patches physico chemical properties and biocompatibility
topic ferroelectric membranes
DLC coatings
vascular patches
url https://www.mdpi.com/2077-0375/11/9/690
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AT elisavetaprosetskaya dlccoatedferroelectricmembranesasvascularpatchesphysicochemicalpropertiesandbiocompatibility
AT evgeniiplotnikov dlccoatedferroelectricmembranesasvascularpatchesphysicochemicalpropertiesandbiocompatibility
AT daryashishkova dlccoatedferroelectricmembranesasvascularpatchesphysicochemicalpropertiesandbiocompatibility
AT yuliakudryavtseva dlccoatedferroelectricmembranesasvascularpatchesphysicochemicalpropertiesandbiocompatibility
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