Case Report: Multilevel Ossification of the Ligamentum Flavum in a Patient With Spinal Osteoblastoma

IntroductionSpinal osteoblastomas are primary benign bone tumors most commonly presenting as diffuse back pain in young adults. Rarely, spinal osteoblastoma is associated with ossification of the ligamentum flavum (OLF), a form of ectopic bone formation, which can present with myelopathy. This repor...

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Main Authors: Canada T. Montgomery, Stephen P. Miranda, Ernest Nelson, Katie Louka, MacLean Nasrallah, Paul J. Zhang, Joel Stein, Dmitriy Petrov
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Surgery
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fsurg.2022.890965/full
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author Canada T. Montgomery
Stephen P. Miranda
Ernest Nelson
Katie Louka
MacLean Nasrallah
Paul J. Zhang
Joel Stein
Dmitriy Petrov
author_facet Canada T. Montgomery
Stephen P. Miranda
Ernest Nelson
Katie Louka
MacLean Nasrallah
Paul J. Zhang
Joel Stein
Dmitriy Petrov
author_sort Canada T. Montgomery
collection DOAJ
description IntroductionSpinal osteoblastomas are primary benign bone tumors most commonly presenting as diffuse back pain in young adults. Rarely, spinal osteoblastoma is associated with ossification of the ligamentum flavum (OLF), a form of ectopic bone formation, which can present with myelopathy. This report highlights a unique case of a patient with spinal osteoblastoma, associated OLF, and thoracic myelopathy.Case DescriptionThe patient presented with subtle myelopathy consisting of mid-thoracic back pain, paresthesias, and gait instability. Imaging findings were suggestive of spinal osteoblastoma with multifocal OLF. The patient was consented for thoracic decompression and stabilization at the T6-10 levels. Histopathology confirmed osteoblastoma with associated OLF. At follow up, the patient’s neurological symptoms had completely resolved.ConclusionThis case describes management for a rare presentation of osteoblastoma with associated OLF and myelopathy. Surgeons should be wary of disproportionate neurological compromise when spinal osteoblastoma is associated with OLF. Further study is required to elucidate the pathogenesis of this condition.
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spelling doaj.art-b22566f9214a4bbaa75b71654efb74c42022-12-22T00:33:10ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2022-06-01910.3389/fsurg.2022.890965890965Case Report: Multilevel Ossification of the Ligamentum Flavum in a Patient With Spinal OsteoblastomaCanada T. Montgomery0Stephen P. Miranda1Ernest Nelson2Katie Louka3MacLean Nasrallah4Paul J. Zhang5Joel Stein6Dmitriy Petrov7University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United StatesDepartment of Neurosurgery, Hospital of the University of Pennsylvania, Philadelphia, PA, United StatesDepartment of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, United StatesDepartment of Pathology, Stony Brook University Hospital, Stony Brook, New York, United StatesDepartment of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, United StatesDepartment of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, United StatesDepartment of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA, United StatesDepartment of Neurosurgery, Hospital of the University of Pennsylvania, Philadelphia, PA, United StatesIntroductionSpinal osteoblastomas are primary benign bone tumors most commonly presenting as diffuse back pain in young adults. Rarely, spinal osteoblastoma is associated with ossification of the ligamentum flavum (OLF), a form of ectopic bone formation, which can present with myelopathy. This report highlights a unique case of a patient with spinal osteoblastoma, associated OLF, and thoracic myelopathy.Case DescriptionThe patient presented with subtle myelopathy consisting of mid-thoracic back pain, paresthesias, and gait instability. Imaging findings were suggestive of spinal osteoblastoma with multifocal OLF. The patient was consented for thoracic decompression and stabilization at the T6-10 levels. Histopathology confirmed osteoblastoma with associated OLF. At follow up, the patient’s neurological symptoms had completely resolved.ConclusionThis case describes management for a rare presentation of osteoblastoma with associated OLF and myelopathy. Surgeons should be wary of disproportionate neurological compromise when spinal osteoblastoma is associated with OLF. Further study is required to elucidate the pathogenesis of this condition.https://www.frontiersin.org/articles/10.3389/fsurg.2022.890965/fullspinal osteoblastomaossification of the ligamentum flavummyelopathyneurosurgeryneurological compromise
spellingShingle Canada T. Montgomery
Stephen P. Miranda
Ernest Nelson
Katie Louka
MacLean Nasrallah
Paul J. Zhang
Joel Stein
Dmitriy Petrov
Case Report: Multilevel Ossification of the Ligamentum Flavum in a Patient With Spinal Osteoblastoma
Frontiers in Surgery
spinal osteoblastoma
ossification of the ligamentum flavum
myelopathy
neurosurgery
neurological compromise
title Case Report: Multilevel Ossification of the Ligamentum Flavum in a Patient With Spinal Osteoblastoma
title_full Case Report: Multilevel Ossification of the Ligamentum Flavum in a Patient With Spinal Osteoblastoma
title_fullStr Case Report: Multilevel Ossification of the Ligamentum Flavum in a Patient With Spinal Osteoblastoma
title_full_unstemmed Case Report: Multilevel Ossification of the Ligamentum Flavum in a Patient With Spinal Osteoblastoma
title_short Case Report: Multilevel Ossification of the Ligamentum Flavum in a Patient With Spinal Osteoblastoma
title_sort case report multilevel ossification of the ligamentum flavum in a patient with spinal osteoblastoma
topic spinal osteoblastoma
ossification of the ligamentum flavum
myelopathy
neurosurgery
neurological compromise
url https://www.frontiersin.org/articles/10.3389/fsurg.2022.890965/full
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