Prevalence and Factors Associated with Delayed Initiation of Antiretroviral Therapy Among People Living with HIV in Nekemte Referral Hospital, Western Ethiopia
Lami Bayisa,1 Abilo Tadesse,1 Mebratu Mitiku Reta,1 Ejigu Gebeye2 1Department of Internal Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia; 2Institute of Public Health, University of Gondar, Gondar, EthiopiaCorrespondence: Abilo Tadesse Email abilo.tadesse@ya...
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| Language: | English |
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Dove Medical Press
2020-09-01
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| Series: | HIV/AIDS: Research and Palliative Care |
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| Online Access: | https://www.dovepress.com/prevalence-and-factors-associated-with-delayed-initiation-of-antiretro-peer-reviewed-article-HIV |
| _version_ | 1818570709444591616 |
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| author | Bayisa L Tadesse A Reta MM Gebeye E |
| author_facet | Bayisa L Tadesse A Reta MM Gebeye E |
| author_sort | Bayisa L |
| collection | DOAJ |
| description | Lami Bayisa,1 Abilo Tadesse,1 Mebratu Mitiku Reta,1 Ejigu Gebeye2 1Department of Internal Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia; 2Institute of Public Health, University of Gondar, Gondar, EthiopiaCorrespondence: Abilo Tadesse Email abilo.tadesse@yahoo.comBackground: Ethiopia has adopted the “Universal Test and Treat” strategy to its national policy in 2016 to put all people living with HIV/AIDS (PLHIV) on antiretroviral therapy (ART) regardless of their World Health Organization (WHO) clinical stage or CD4 cell count level. A significant percentage of PLHIV start therapy has been delayed despite the availability of ART, which results in poor treatment outcomes including HIV-related morbidity and mortality, and continued HIV transmission.Methods: This cross-sectional study was conducted to determine the magnitude and associated factors of delayed ART initiation among PLHIV at ART Clinic, Nekemte Referral hospital, Western Ethiopia between January 1, 2020 and March 31, 2020 for the time period of January 1, 2016 to December 31, 2019. A consecutive sampling method was used to recruit 417 study subjects. The collected data were entered into Epi data version 3.1 and exported to STATA version 14 for statistical analysis. Logistic regression analysis was used to identify associated factors with delayed ART initiation among PLHIV. P-values< 0.05 were used to declare significant association.Results: A total of 417 PLHIV were included in the study. The mean age of study subjects was 33.49 (SD± 9.81) years. The majority of participants attended formal education (77%) and were urban dwellers (82%). One-third (34%) of them initiated ART delayed, beyond 7 days of confirmed HIV diagnosis. Subjects with normal nutritional status (BMI=18.5– 24.9kg/m2) (AOR=3.12, 95% CI=1.29– 7.57; P=0.012), CD4 count ≥ 351cells/mm3 (AOR=2.89, 95% CI=1.27– 6.58; P=0.011), tuberculosis (TBC) co-infection (AOR=2.76, 95% CI=1.13– 6.70; P=0.025), use of traditional treatment (AOR=4.03, 95% CI=2.03– 8.00; P< 0.001) and did not know other ART user(s) (AOR=2.86, 95% CI=1.52– 5.37; P=0.001) were significantly associated with delayed ART initiation.Conclusion: Early HIV testing mechanisms and timely linkage to HIV care by advocating “Test-and-Treat” should be strengthened.Keywords: PLHIV, antiretroviral therapy, Western Ethiopia |
| first_indexed | 2024-12-14T13:45:30Z |
| format | Article |
| id | doaj.art-b22f9241536c4ad983f7f50bc96c0ec1 |
| institution | Directory Open Access Journal |
| issn | 1179-1373 |
| language | English |
| last_indexed | 2024-12-14T13:45:30Z |
| publishDate | 2020-09-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | HIV/AIDS: Research and Palliative Care |
| spelling | doaj.art-b22f9241536c4ad983f7f50bc96c0ec12022-12-21T22:59:20ZengDove Medical PressHIV/AIDS: Research and Palliative Care1179-13732020-09-01Volume 1245746557309Prevalence and Factors Associated with Delayed Initiation of Antiretroviral Therapy Among People Living with HIV in Nekemte Referral Hospital, Western EthiopiaBayisa LTadesse AReta MMGebeye ELami Bayisa,1 Abilo Tadesse,1 Mebratu Mitiku Reta,1 Ejigu Gebeye2 1Department of Internal Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia; 2Institute of Public Health, University of Gondar, Gondar, EthiopiaCorrespondence: Abilo Tadesse Email abilo.tadesse@yahoo.comBackground: Ethiopia has adopted the “Universal Test and Treat” strategy to its national policy in 2016 to put all people living with HIV/AIDS (PLHIV) on antiretroviral therapy (ART) regardless of their World Health Organization (WHO) clinical stage or CD4 cell count level. A significant percentage of PLHIV start therapy has been delayed despite the availability of ART, which results in poor treatment outcomes including HIV-related morbidity and mortality, and continued HIV transmission.Methods: This cross-sectional study was conducted to determine the magnitude and associated factors of delayed ART initiation among PLHIV at ART Clinic, Nekemte Referral hospital, Western Ethiopia between January 1, 2020 and March 31, 2020 for the time period of January 1, 2016 to December 31, 2019. A consecutive sampling method was used to recruit 417 study subjects. The collected data were entered into Epi data version 3.1 and exported to STATA version 14 for statistical analysis. Logistic regression analysis was used to identify associated factors with delayed ART initiation among PLHIV. P-values< 0.05 were used to declare significant association.Results: A total of 417 PLHIV were included in the study. The mean age of study subjects was 33.49 (SD± 9.81) years. The majority of participants attended formal education (77%) and were urban dwellers (82%). One-third (34%) of them initiated ART delayed, beyond 7 days of confirmed HIV diagnosis. Subjects with normal nutritional status (BMI=18.5– 24.9kg/m2) (AOR=3.12, 95% CI=1.29– 7.57; P=0.012), CD4 count ≥ 351cells/mm3 (AOR=2.89, 95% CI=1.27– 6.58; P=0.011), tuberculosis (TBC) co-infection (AOR=2.76, 95% CI=1.13– 6.70; P=0.025), use of traditional treatment (AOR=4.03, 95% CI=2.03– 8.00; P< 0.001) and did not know other ART user(s) (AOR=2.86, 95% CI=1.52– 5.37; P=0.001) were significantly associated with delayed ART initiation.Conclusion: Early HIV testing mechanisms and timely linkage to HIV care by advocating “Test-and-Treat” should be strengthened.Keywords: PLHIV, antiretroviral therapy, Western Ethiopiahttps://www.dovepress.com/prevalence-and-factors-associated-with-delayed-initiation-of-antiretro-peer-reviewed-article-HIVplhivantiretroviral therapywestern ethiopia |
| spellingShingle | Bayisa L Tadesse A Reta MM Gebeye E Prevalence and Factors Associated with Delayed Initiation of Antiretroviral Therapy Among People Living with HIV in Nekemte Referral Hospital, Western Ethiopia HIV/AIDS: Research and Palliative Care plhiv antiretroviral therapy western ethiopia |
| title | Prevalence and Factors Associated with Delayed Initiation of Antiretroviral Therapy Among People Living with HIV in Nekemte Referral Hospital, Western Ethiopia |
| title_full | Prevalence and Factors Associated with Delayed Initiation of Antiretroviral Therapy Among People Living with HIV in Nekemte Referral Hospital, Western Ethiopia |
| title_fullStr | Prevalence and Factors Associated with Delayed Initiation of Antiretroviral Therapy Among People Living with HIV in Nekemte Referral Hospital, Western Ethiopia |
| title_full_unstemmed | Prevalence and Factors Associated with Delayed Initiation of Antiretroviral Therapy Among People Living with HIV in Nekemte Referral Hospital, Western Ethiopia |
| title_short | Prevalence and Factors Associated with Delayed Initiation of Antiretroviral Therapy Among People Living with HIV in Nekemte Referral Hospital, Western Ethiopia |
| title_sort | prevalence and factors associated with delayed initiation of antiretroviral therapy among people living with hiv in nekemte referral hospital western ethiopia |
| topic | plhiv antiretroviral therapy western ethiopia |
| url | https://www.dovepress.com/prevalence-and-factors-associated-with-delayed-initiation-of-antiretro-peer-reviewed-article-HIV |
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