Identification of Host Kinase Genes Required for Influenza Virus Replication and the Regulatory Role of MicroRNAs.

Identification of Host Kinase Genes Required for Influenza Virus Replication and the Regulatory Role of MicroRNAs.

Human protein kinases (HPKs) have profound effects on cellular responses. To better understand the role of HPKs and the signaling networks that influence influenza virus replication, a small interfering RNA (siRNA) screen of 720 HPKs was performed. From the screen, 17 HPKs (NPR2, MAP3K1, DYRK3, EPHA...

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Bibliographic Details
Main Authors: Abhijeet Bakre, Lauren E Andersen, Victoria Meliopoulos, Keegan Coleman, Xiuzhen Yan, Paula Brooks, Jackelyn Crabtree, S Mark Tompkins, Ralph A Tripp
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3689682?pdf=render

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