PHFinder: assisted detection of point heteroplasmy in Sanger sequencing chromatograms

PHFinder: assisted detection of point heteroplasmy in Sanger sequencing chromatograms

Heteroplasmy is the presence of two or more organellar genomes (mitochondrial or plastid DNA) in an organism, tissue, cell or organelle. Heteroplasmy can be detected by visual inspection of Sanger sequencing chromatograms, where it appears as multiple peaks of fluorescence at a single nucleotide pos...

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Bibliographic Details
Main Authors: Marcos Suárez Menéndez, Vania E. Rivera-León, Jooke Robbins, Martine Berube, Per J. Palsbøll
Format: Article
Language:English
Published: PeerJ Inc. 2023-09-01
Series:PeerJ
Subjects:
Chromatograms
Detection
Heteroplasmy
Sanger
Software
AB1
Online Access:https://peerj.com/articles/16028.pdf

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