INTRAARTICULAR KNEE JOINT INJECTION: HYALURONIC ACID VS POLYNUCLEOTIDES
This study is a retrospective work of ambulatorial injections in patients suffering from Class II osteoarthritis (OA) of the knee. The research was conducted from January 2012 to July 2012 in a private clinic in Benevento, Hospital Val D'Elsa, Poggibonsi, Siena. A total of 60 patients were t...
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| Format: | Article |
| Language: | English |
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Associazione Italiana Giovani Medici
2013-04-01
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| Series: | Euromediterranean Biomedical Journal |
| Online Access: | http://www.embj.org/images/ISSUE_2013/meccariello_7.pdf |
| Summary: | This study is a retrospective work of ambulatorial injections in patients suffering from
Class II osteoarthritis (OA) of the knee. The research was conducted from January 2012 to
July 2012 in a private clinic in Benevento, Hospital Val D'Elsa, Poggibonsi, Siena. A total of
60 patients were treated with intraarticular knee injections. Group A, composed of 30
patients (15 male and 15 female), was treated with injections of low molecular weight
Hyaluronic Acid and Group B, composed of 30 patients (15 male and 15 female) was
treated with injections of Ploynucleotide. At the six month follow-up, Group B showed a
statistically significant difference (p<0.05) of the Visual Analogue Scale (VAS); the Knee
injury and Osteoarthritis Outcome Score for Group B also showed a statistically significant
difference (p<0.05). The results obtained suggest that polynucleotides can be considered
as a valid alternative to hyaluronic acid for the treatment of symptomatic osteoarthritis of
the knee. |
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| ISSN: | 2279-7165 2279-7165 |