Quantitative Characterization of CD8+ T Cell Clustering and Spatial Heterogeneity in Solid Tumors

Quantitative Characterization of CD8+ T Cell Clustering and Spatial Heterogeneity in Solid Tumors

Quantitative characterization of the tumor microenvironment, including its immuno-architecture, is important for developing quantitative diagnostic and predictive biomarkers, matching patients to the most appropriate treatments for precision medicine, and for providing quantitative data for building...

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Bibliographic Details
Main Authors:	Chang Gong, Robert A. Anders, Qingfeng Zhu, Janis M. Taube, Benjamin Green, Wenting Cheng, Imke H. Bartelink, Paolo Vicini, Bing Wang, Aleksander S. Popel
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2019-01-01
Series:	Frontiers in Oncology
Subjects:	digital pathology spatial patterns spatial statistics immuno-architecture systems biology
Online Access:	https://www.frontiersin.org/article/10.3389/fonc.2018.00649/full

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