Selenocystine-Derived Label-Free Fluorescent Schiff Base Nanocomplex for siRNA Delivery Synergistically Kills Cancer Cells

Selenocystine-Derived Label-Free Fluorescent Schiff Base Nanocomplex for siRNA Delivery Synergistically Kills Cancer Cells

Chemo and siRNA synergic treatments for tumors is a promising new therapeutic trend. Selenocystine, a selenium analog of cysteine, has been considered a potential antitumor agent due to its redox perturbing role. In this study, we developed a nanocarrier for siRNA based on a selenocystine analog eng...

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Bibliographic Details
Main Authors: Yang Liu, Haoying Yang, Qian Liu, Mingming Pan, Danli Wang, Shiyuan Pan, Weiran Zhang, Jinfeng Wei, Xiaowei Zhao, Junfeng Ji
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Molecules
Subjects:
selenocystine
fluorescent Schiff base
Schiff base probe
siRNA nanoparticle
tumor senescence
Online Access:https://www.mdpi.com/1420-3049/27/4/1302

Internet

https://www.mdpi.com/1420-3049/27/4/1302

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