Predicting lung adenocarcinoma disease progression using methylation-correlated blocks and ensemble machine learning classifiers
Applying the knowledge that methyltransferases and demethylases can modify adjacent cytosine-phosphorothioate-guanine (CpG) sites in the same DNA strand, we found that combining multiple CpGs into a single block may improve cancer diagnosis. However, survival prediction remains a challenge. In this...
Main Authors: | Xin Yu, Qian Yang, Dong Wang, Zhaoyang Li, Nianhang Chen, De-Xin Kong |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2021-02-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/10884.pdf |
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