Predicting lung adenocarcinoma disease progression using methylation-correlated blocks and ensemble machine learning classifiers

Applying the knowledge that methyltransferases and demethylases can modify adjacent cytosine-phosphorothioate-guanine (CpG) sites in the same DNA strand, we found that combining multiple CpGs into a single block may improve cancer diagnosis. However, survival prediction remains a challenge. In this...

Full description

Bibliographic Details
Main Authors: Xin Yu, Qian Yang, Dong Wang, Zhaoyang Li, Nianhang Chen, De-Xin Kong
Format: Article
Language:English
Published: PeerJ Inc. 2021-02-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/10884.pdf

Similar Items