The ESX-3 secretion system is necessary for iron and zinc homeostasis in Mycobacterium tuberculosis.

The ESX-3 secretion system is necessary for iron and zinc homeostasis in Mycobacterium tuberculosis.

ESX-3 is one of the five type VII secretion systems encoded by the Mycobacterium tuberculosis genome. We recently showed the essentiality of ESX-3 for M. tuberculosis viability and proposed its involvement in iron and zinc metabolism. In this study we confirmed the role of ESX-3 in iron uptake and i...

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Bibliographic Details
Main Authors: Agnese Serafini, Davide Pisu, Giorgio Palù, G Marcela Rodriguez, Riccardo Manganelli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3796483?pdf=render

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