Solitary fibrous tumor of the tongue
Solitary fibrous tumor (SFT) is a benign mesenchymal neoplasm originally described in pleura with a rare presentation in the oral cavity. Herein, we report a case of a 28-year-old male patient who presented an asymptomatic slow-growing mass in the anterior part of the tongue. Intraoral examination...
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| Format: | Article |
| Language: | English |
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University of São Paulo
2022-11-01
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| Series: | Autopsy and Case Reports |
| Subjects: | |
| Online Access: | https://www.revistas.usp.br/autopsy/article/view/204725 |
| _version_ | 1811189099944476672 |
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| author | Juliana Mota Siqueira Daniele Heguedusch Emília Maria Gomes Aguiar Anaeliza Figueiredo dos Santos Fabio Abreu Alves Fabio Daumas Nunes |
| author_facet | Juliana Mota Siqueira Daniele Heguedusch Emília Maria Gomes Aguiar Anaeliza Figueiredo dos Santos Fabio Abreu Alves Fabio Daumas Nunes |
| author_sort | Juliana Mota Siqueira |
| collection | DOAJ |
| description |
Solitary fibrous tumor (SFT) is a benign mesenchymal neoplasm originally described in pleura with a rare presentation in the oral cavity. Herein, we report a case of a 28-year-old male patient who presented an asymptomatic slow-growing mass in the anterior part of the tongue. Intraoral examination revealed a well-circumscribed mass covered by normal mucosa with a fibrous consistency. Due to non-specific clinical findings, the initial diagnostic hypotheses include benign submucosal neoplasms such as leiomyoma, neurofibroma, SFT, and others. An excisional biopsy was performed. Microscopically, the tumor was surrounded by a thick fibrous capsule; hypo and hypercellular areas were arranged in a storiform pattern with a stroma formed by collagen and abundant vascularization. Tumor cells showed immunopositivity for CD34 and STAT-6 and no expression of CD99, AML, S-100, and Ki-67. According to these findings, the diagnosis of SFT was established. After 24 months, the patient is asymptomatic and has no evidence of recurrence. Although oral involvement is rare, SFT should be included in the differential diagnosis of oral submucosal lesions.
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| first_indexed | 2024-04-11T14:28:58Z |
| format | Article |
| id | doaj.art-b23fa11d0cff4ad18196e9294f9fd1bd |
| institution | Directory Open Access Journal |
| issn | 2236-1960 |
| language | English |
| last_indexed | 2024-04-11T14:28:58Z |
| publishDate | 2022-11-01 |
| publisher | University of São Paulo |
| record_format | Article |
| series | Autopsy and Case Reports |
| spelling | doaj.art-b23fa11d0cff4ad18196e9294f9fd1bd2022-12-22T04:18:42ZengUniversity of São PauloAutopsy and Case Reports2236-19602022-11-0112Solitary fibrous tumor of the tongueJuliana Mota Siqueira0Daniele Heguedusch1Emília Maria Gomes Aguiar2Anaeliza Figueiredo dos Santos3Fabio Abreu Alves4Fabio Daumas Nunes5Universidade de São Paulo (USP), Dental School, Department of Oral and Maxillofacial Pathology, São Paulo, SP, BrasilUniversidade de São Paulo (USP), Dental School, Department of Oral and Maxillofacial Pathology, São Paulo, SP, BrasilUniversidade de São Paulo (USP), Dental School, Department of Oral and Maxillofacial Pathology, São Paulo, SP, BrasilUniversidade de São Paulo (USP), Dental School, Department of Oral and Maxillofacial Pathology, São Paulo, SP, BrasilUniversidade de São Paulo (USP), Dental School, Stomatology Department, São Paulo, SP, Brasil,A.C. Camargo Cancer Center, Stomatology Department, São Paulo, SP, BrasilUniversidade de São Paulo (USP), Dental School, Department of Oral and Maxillofacial Pathology, São Paulo, SP, Brasil Solitary fibrous tumor (SFT) is a benign mesenchymal neoplasm originally described in pleura with a rare presentation in the oral cavity. Herein, we report a case of a 28-year-old male patient who presented an asymptomatic slow-growing mass in the anterior part of the tongue. Intraoral examination revealed a well-circumscribed mass covered by normal mucosa with a fibrous consistency. Due to non-specific clinical findings, the initial diagnostic hypotheses include benign submucosal neoplasms such as leiomyoma, neurofibroma, SFT, and others. An excisional biopsy was performed. Microscopically, the tumor was surrounded by a thick fibrous capsule; hypo and hypercellular areas were arranged in a storiform pattern with a stroma formed by collagen and abundant vascularization. Tumor cells showed immunopositivity for CD34 and STAT-6 and no expression of CD99, AML, S-100, and Ki-67. According to these findings, the diagnosis of SFT was established. After 24 months, the patient is asymptomatic and has no evidence of recurrence. Although oral involvement is rare, SFT should be included in the differential diagnosis of oral submucosal lesions. https://www.revistas.usp.br/autopsy/article/view/204725Solitary Fibrous Tumors; Oral diagnosis; Oral Pathology |
| spellingShingle | Juliana Mota Siqueira Daniele Heguedusch Emília Maria Gomes Aguiar Anaeliza Figueiredo dos Santos Fabio Abreu Alves Fabio Daumas Nunes Solitary fibrous tumor of the tongue Autopsy and Case Reports Solitary Fibrous Tumors; Oral diagnosis; Oral Pathology |
| title | Solitary fibrous tumor of the tongue |
| title_full | Solitary fibrous tumor of the tongue |
| title_fullStr | Solitary fibrous tumor of the tongue |
| title_full_unstemmed | Solitary fibrous tumor of the tongue |
| title_short | Solitary fibrous tumor of the tongue |
| title_sort | solitary fibrous tumor of the tongue |
| topic | Solitary Fibrous Tumors; Oral diagnosis; Oral Pathology |
| url | https://www.revistas.usp.br/autopsy/article/view/204725 |
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