Perivascular cell‐derived extracellular vesicles stimulate colorectal cancer revascularization after withdrawal of antiangiogenic drugs

Perivascular cell‐derived extracellular vesicles stimulate colorectal cancer revascularization after withdrawal of antiangiogenic drugs

Abstract Antiangiogenic tyrosine kinase inhibitors (AA‐TKIs) have become a promising therapeutic strategy for colorectal cancer (CRC). In clinical practice, a significant proportion of cancer patients temporarily discontinue AA‐TKI treatment due to recurrent toxicities, economic burden or acquired r...

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Bibliographic Details
Main Authors: Maohua Huang, Minfeng Chen, Ming Qi, Geni Ye, Jinghua Pan, Changzheng Shi, Yunlong Yang, Luyu Zhao, Xukai Mo, Yiran Zhang, Yong Li, Jincheng Zhong, Weijin Lu, Xiaobo Li, Jiayan Zhang, Jinrong Lin, Liangping Luo, Tongzheng Liu, Patrick Ming‐Kuen Tang, An Hong, Yihai Cao, Wencai Ye, Dongmei Zhang
Format: Article
Language:English
Published: Wiley 2021-05-01
Series:Journal of Extracellular Vesicles
Subjects:
antiangiogenic therapy
endothelial progenitor cell
extracellular vesicle
perivascular cell
tyrosine kinase inhibitor
Online Access:https://doi.org/10.1002/jev2.12096

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