Feasibility of Using Fat Degeneration of Lumbar Extensor Muscle as an Alternative Diagnostic Criterion for Sarcopenia in Patients with Osteoporotic Vertebral Fractures
Study Design Feasibility study. Purpose To investigate the feasibility of using fat degeneration of lumbar extensor muscle (LEM) as an alternative diagnostic criterion for sarcopenia in patients with osteoporotic vertebral fractures. Overview of Literature Although sarcopenia has been gaining increa...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Korean Spine Society
2020-06-01
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| Series: | Asian Spine Journal |
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| Online Access: | http://www.asianspinejournal.org/upload/pdf/asj-2019-0044.pdf |
| _version_ | 1818260404490469376 |
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| author | Ju-Yeong Heo Ji-Hun Park Sung-An Lim Seung-Woo Shim Yong-Soo Choi |
| author_facet | Ju-Yeong Heo Ji-Hun Park Sung-An Lim Seung-Woo Shim Yong-Soo Choi |
| author_sort | Ju-Yeong Heo |
| collection | DOAJ |
| description | Study Design Feasibility study. Purpose To investigate the feasibility of using fat degeneration of lumbar extensor muscle (LEM) as an alternative diagnostic criterion for sarcopenia in patients with osteoporotic vertebral fractures. Overview of Literature Although sarcopenia has been gaining increased attention among researchers and healthcare practitioners, there is uncertainty about the association between sarcopenia and fat degeneration of LEM. Methods In this study, 33 patients with osteoporotic vertebral fractures (group 1) and 29 patients without such fractures (group 2) were enrolled. Sarcopenia was diagnosed in accordance with the Asian Working Group for Sarcopenia (AWGS) criteria, including assessment of extremity muscle mass using dual-energy X-ray absorptiometry, grip strength, and gait speed. The bone mineral density and fat degeneration of LEM were investigated using magnetic resonance imaging. Results The mean rates of fat degeneration of LEM and the skeletal muscle index were 38.3% and 5.5 kg/m2 in group 1 and 28.9% and 6.3 kg/m2 in group 2, respectively. The fat degeneration of LEM was negatively correlated with gait speed (r=−0.44, p=0.01) and handgrip strength (r=−0.37, p=0.01). The fat degeneration of LEM also demonstrated a significant relationship with osteoporotic vertebral fractures (p=0.01). Receiver operating characteristic curve analysis between fat degeneration of LEM and osteoporotic vertebral fractures showed that the cut-off value of fat degeneration was 31.9% (sensitivity=0.67, specificity=0.66). There was a positive correlation between sarcopenia defined by the AWGS and that defined by the 31.90% cut-off value of fat degeneration of LEM instead of extremity muscle mass (r=0.46, p=0.01). Conclusions These results suggest the feasibility of using fat degeneration of LEM as an alternative diagnostic criterion for sarcopenia in patients with osteoporotic vertebral fractures. A cut-off value of fat degeneration of LEM of 31.9% was shown to be useful for diagnosing osteoporotic vertebral fractures. |
| first_indexed | 2024-12-12T18:30:48Z |
| format | Article |
| id | doaj.art-b241b8d1184a48028655ad613306668d |
| institution | Directory Open Access Journal |
| issn | 1976-1902 1976-7846 |
| language | English |
| last_indexed | 2024-12-12T18:30:48Z |
| publishDate | 2020-06-01 |
| publisher | Korean Spine Society |
| record_format | Article |
| series | Asian Spine Journal |
| spelling | doaj.art-b241b8d1184a48028655ad613306668d2022-12-22T00:15:55ZengKorean Spine SocietyAsian Spine Journal1976-19021976-78462020-06-0114332032610.31616/asj.2019.00441139Feasibility of Using Fat Degeneration of Lumbar Extensor Muscle as an Alternative Diagnostic Criterion for Sarcopenia in Patients with Osteoporotic Vertebral FracturesJu-Yeong Heo0Ji-Hun ParkSung-An Lim1Seung-Woo Shim2Yong-Soo Choi3 Department of Orthopedic Surgery, Kwangju Christian Hospital, Gwangju, Korea Department of Orthopedic Surgery, Kwangju Christian Hospital, Gwangju, Korea Department of Orthopedic Surgery, Kwangju Christian Hospital, Gwangju, Korea Department of Orthopedic Surgery, Kwangju Christian Hospital, Gwangju, KoreaStudy Design Feasibility study. Purpose To investigate the feasibility of using fat degeneration of lumbar extensor muscle (LEM) as an alternative diagnostic criterion for sarcopenia in patients with osteoporotic vertebral fractures. Overview of Literature Although sarcopenia has been gaining increased attention among researchers and healthcare practitioners, there is uncertainty about the association between sarcopenia and fat degeneration of LEM. Methods In this study, 33 patients with osteoporotic vertebral fractures (group 1) and 29 patients without such fractures (group 2) were enrolled. Sarcopenia was diagnosed in accordance with the Asian Working Group for Sarcopenia (AWGS) criteria, including assessment of extremity muscle mass using dual-energy X-ray absorptiometry, grip strength, and gait speed. The bone mineral density and fat degeneration of LEM were investigated using magnetic resonance imaging. Results The mean rates of fat degeneration of LEM and the skeletal muscle index were 38.3% and 5.5 kg/m2 in group 1 and 28.9% and 6.3 kg/m2 in group 2, respectively. The fat degeneration of LEM was negatively correlated with gait speed (r=−0.44, p=0.01) and handgrip strength (r=−0.37, p=0.01). The fat degeneration of LEM also demonstrated a significant relationship with osteoporotic vertebral fractures (p=0.01). Receiver operating characteristic curve analysis between fat degeneration of LEM and osteoporotic vertebral fractures showed that the cut-off value of fat degeneration was 31.9% (sensitivity=0.67, specificity=0.66). There was a positive correlation between sarcopenia defined by the AWGS and that defined by the 31.90% cut-off value of fat degeneration of LEM instead of extremity muscle mass (r=0.46, p=0.01). Conclusions These results suggest the feasibility of using fat degeneration of LEM as an alternative diagnostic criterion for sarcopenia in patients with osteoporotic vertebral fractures. A cut-off value of fat degeneration of LEM of 31.9% was shown to be useful for diagnosing osteoporotic vertebral fractures.http://www.asianspinejournal.org/upload/pdf/asj-2019-0044.pdfvertebral fracturespinal fractureslumbar extensor muscleback muscles |
| spellingShingle | Ju-Yeong Heo Ji-Hun Park Sung-An Lim Seung-Woo Shim Yong-Soo Choi Feasibility of Using Fat Degeneration of Lumbar Extensor Muscle as an Alternative Diagnostic Criterion for Sarcopenia in Patients with Osteoporotic Vertebral Fractures Asian Spine Journal vertebral fracture spinal fractures lumbar extensor muscle back muscles |
| title | Feasibility of Using Fat Degeneration of Lumbar Extensor Muscle as an Alternative Diagnostic Criterion for Sarcopenia in Patients with Osteoporotic Vertebral Fractures |
| title_full | Feasibility of Using Fat Degeneration of Lumbar Extensor Muscle as an Alternative Diagnostic Criterion for Sarcopenia in Patients with Osteoporotic Vertebral Fractures |
| title_fullStr | Feasibility of Using Fat Degeneration of Lumbar Extensor Muscle as an Alternative Diagnostic Criterion for Sarcopenia in Patients with Osteoporotic Vertebral Fractures |
| title_full_unstemmed | Feasibility of Using Fat Degeneration of Lumbar Extensor Muscle as an Alternative Diagnostic Criterion for Sarcopenia in Patients with Osteoporotic Vertebral Fractures |
| title_short | Feasibility of Using Fat Degeneration of Lumbar Extensor Muscle as an Alternative Diagnostic Criterion for Sarcopenia in Patients with Osteoporotic Vertebral Fractures |
| title_sort | feasibility of using fat degeneration of lumbar extensor muscle as an alternative diagnostic criterion for sarcopenia in patients with osteoporotic vertebral fractures |
| topic | vertebral fracture spinal fractures lumbar extensor muscle back muscles |
| url | http://www.asianspinejournal.org/upload/pdf/asj-2019-0044.pdf |
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