Applications of iPSC-derived beta cells from patients with diabetes

Applications of iPSC-derived beta cells from patients with diabetes

Summary: Improved stem cell-derived pancreatic islet (SC-islet) differentiation protocols robustly generate insulin-secreting β cells from patient induced pluripotent stem cells (iPSCs). These advances are enabling in vitro disease modeling studies and the development of an autologous diabetes cell...

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Bibliographic Details
Main Authors: Kristina G. Maxwell, Jeffrey R. Millman
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Cell Reports Medicine
Subjects:
diabetes
stem cells
differentiation
disease modeling
cell therapy
CRISPR
Online Access:http://www.sciencedirect.com/science/article/pii/S2666379121000549

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