Are Hematological Parameters Useful in Assessing Disease Activity in Chronic Otitis Media?
Aim:To investigate the role of hematological parameters in assessing disease activity of chronic otitis media (COM).Methods:Patients who underwent surgery for COM between 2014 and 2018 were examined retrospectively. The patients were divided into active and inactive COM groups. Active group was divi...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2020-01-01
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| Series: | Haseki Tıp Bülteni |
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http://www.hasekidergisi.com/archives/archive-detail/article-preview/are-hematological-parameters-useful-in-assessing-d/35951
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| _version_ | 1797920663161274368 |
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| author | Fazilet Altın Yalçın Alimoğlu |
| author_facet | Fazilet Altın Yalçın Alimoğlu |
| author_sort | Fazilet Altın |
| collection | DOAJ |
| description | Aim:To investigate the role of hematological parameters in assessing disease activity of chronic otitis media (COM).Methods:Patients who underwent surgery for COM between 2014 and 2018 were examined retrospectively. The patients were divided into active and inactive COM groups. Active group was divided into cholesteatoma, granulation tissue, and cholesteatoma + granulation tissue subgroups. Inactive group was divided into tympanosclerosis and normal middle ear mucosa subgroups. Preoperative complete blood count parameters were examined retrospectively. Neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and mean platelet volume (MPV) in active and inactive groups and also the values in subgroups of each group were compared.Results:Our study contained 1126 patients. There were 558 (49.55%) male, 568 (50.45%) female patients. The mean age was 31±14.93 (7-74) years. Active and inactive groups consisted of 329 (29.22%) and 797 (70.78%) patients, respectively. There was no significant difference between active and inactive COM groups in terms of NLR (p=0.234), PLR (p=0.733) and MPV (p=0.992). There was no significant difference among subgroups of active and inactive groups (p>0.05). Receiver operating characteristic curve analysis for NLR, PLR and MPV in the groups revealed no cut-off value for differentiating any group from another (p>0.05).Conclusion:NLR, PLR, and MPV values do not have any significant value in the assessment of disease activity of COM. |
| first_indexed | 2024-04-10T14:04:34Z |
| format | Article |
| id | doaj.art-b241e62d4aaa4a76a19053642720d172 |
| institution | Directory Open Access Journal |
| issn | 1302-0072 2147-2688 |
| language | English |
| last_indexed | 2024-04-10T14:04:34Z |
| publishDate | 2020-01-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Haseki Tıp Bülteni |
| spelling | doaj.art-b241e62d4aaa4a76a19053642720d1722023-02-15T16:10:03ZengGalenos YayineviHaseki Tıp Bülteni1302-00722147-26882020-01-01581525610.4274/haseki.galenos.2019.562413049054Are Hematological Parameters Useful in Assessing Disease Activity in Chronic Otitis Media?Fazilet Altın0Yalçın Alimoğlu1 University of Health Sciences, Haseki Training and Research Hospital, Clinic of Otolaryngology, İstanbul, Turkey University of Health Sciences, Haseki Training and Research Hospital, Clinic of Otolaryngology, İstanbul, Turkey Aim:To investigate the role of hematological parameters in assessing disease activity of chronic otitis media (COM).Methods:Patients who underwent surgery for COM between 2014 and 2018 were examined retrospectively. The patients were divided into active and inactive COM groups. Active group was divided into cholesteatoma, granulation tissue, and cholesteatoma + granulation tissue subgroups. Inactive group was divided into tympanosclerosis and normal middle ear mucosa subgroups. Preoperative complete blood count parameters were examined retrospectively. Neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and mean platelet volume (MPV) in active and inactive groups and also the values in subgroups of each group were compared.Results:Our study contained 1126 patients. There were 558 (49.55%) male, 568 (50.45%) female patients. The mean age was 31±14.93 (7-74) years. Active and inactive groups consisted of 329 (29.22%) and 797 (70.78%) patients, respectively. There was no significant difference between active and inactive COM groups in terms of NLR (p=0.234), PLR (p=0.733) and MPV (p=0.992). There was no significant difference among subgroups of active and inactive groups (p>0.05). Receiver operating characteristic curve analysis for NLR, PLR and MPV in the groups revealed no cut-off value for differentiating any group from another (p>0.05).Conclusion:NLR, PLR, and MPV values do not have any significant value in the assessment of disease activity of COM. http://www.hasekidergisi.com/archives/archive-detail/article-preview/are-hematological-parameters-useful-in-assessing-d/35951 chronic otitis mediadisease activityhematological parameter |
| spellingShingle | Fazilet Altın Yalçın Alimoğlu Are Hematological Parameters Useful in Assessing Disease Activity in Chronic Otitis Media? Haseki Tıp Bülteni chronic otitis media disease activity hematological parameter |
| title | Are Hematological Parameters Useful in Assessing Disease Activity in Chronic Otitis Media? |
| title_full | Are Hematological Parameters Useful in Assessing Disease Activity in Chronic Otitis Media? |
| title_fullStr | Are Hematological Parameters Useful in Assessing Disease Activity in Chronic Otitis Media? |
| title_full_unstemmed | Are Hematological Parameters Useful in Assessing Disease Activity in Chronic Otitis Media? |
| title_short | Are Hematological Parameters Useful in Assessing Disease Activity in Chronic Otitis Media? |
| title_sort | are hematological parameters useful in assessing disease activity in chronic otitis media |
| topic | chronic otitis media disease activity hematological parameter |
| url |
http://www.hasekidergisi.com/archives/archive-detail/article-preview/are-hematological-parameters-useful-in-assessing-d/35951
|
| work_keys_str_mv | AT faziletaltın arehematologicalparametersusefulinassessingdiseaseactivityinchronicotitismedia AT yalcınalimoglu arehematologicalparametersusefulinassessingdiseaseactivityinchronicotitismedia |