Extracellular Matrix Expression in Human Pancreatic Fat Cells of Patients with Normal Glucose Regulation, Prediabetes and Type 2 Diabetes

Extracellular Matrix Expression in Human Pancreatic Fat Cells of Patients with Normal Glucose Regulation, Prediabetes and Type 2 Diabetes

Previously, we found that human pancreatic preadipocytes (PPAs) and islets influence each other and that the crosstalk with the fatty liver via the hepatokine fetuin-A/palmitate induces inflammatory responses. Here, we examined whether the mRNA-expression of pancreatic extracellular matrix (ECM)-for...

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Bibliographic Details
Main Authors: Dorothea Siegel-Axel, Morgana Barroso Oquendo, Felicia Gerst, Falko Fend, Robert Wagner, Martin Heni, Alfred Königsrainer, Hans-Ulrich Häring, Andreas Fritsche, Erwin Schleicher, Andreas L. Birkenfeld, Norbert Stefan
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:International Journal of Molecular Sciences
Subjects:
(pre)adipocytes
islets
fetuin-A
monocytes
extracellular matrix
adipose tissue
Online Access:https://www.mdpi.com/1422-0067/24/13/11169

Internet

https://www.mdpi.com/1422-0067/24/13/11169

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