Positive predictive value of ICD-10 diagnosis codes for brain abscess in the Danish National Patient Registry
Jacob Bodilsen,1 Michael Dalager-Pedersen,1 Nicolai Kjærgaard,1 Diederik van de Beek,2 Matthijs C Brouwer,2 Henrik Nielsen,1 and the DASGIB study group 1Department of Infectious Diseases, Aalborg University Hospital, Aalborg, Denmark; 2Department of Neurology, Amsterdam Neuroscience, Acade...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2018-10-01
|
| Series: | Clinical Epidemiology |
| Subjects: | |
| Online Access: | https://www.dovepress.com/positive-predictive-value-of-icd-10-diagnosis-codes-for-brain-abscess--peer-reviewed-article-CLEP |
| _version_ | 1811237101979566080 |
|---|---|
| author | Bodilsen J Dalager-Pedersen M Kjærgaard N van de Beek D Brouwer MC Nielsen H |
| author_facet | Bodilsen J Dalager-Pedersen M Kjærgaard N van de Beek D Brouwer MC Nielsen H |
| author_sort | Bodilsen J |
| collection | DOAJ |
| description | Jacob Bodilsen,1 Michael Dalager-Pedersen,1 Nicolai Kjærgaard,1 Diederik van de Beek,2 Matthijs C Brouwer,2 Henrik Nielsen,1 and the DASGIB study group 1Department of Infectious Diseases, Aalborg University Hospital, Aalborg, Denmark; 2Department of Neurology, Amsterdam Neuroscience, Academic Medical Centre, Amsterdam, The Netherlands Purpose: To evaluate the positive predictive value (PPV) of ICD-10 diagnosis codes for brain abscess in the Danish National Patient Registry (DNPR). Patients and methods: We examined medical records of all patients with a first-time diagnosis code of brain abscess in the DNPR from 2007 to 2016. Patients were categorized with either confirmed or disproved brain abscess using a priori defined criteria. We computed the PPV as the proportion of confirmed diagnoses. Results: We identified 709 patients, of whom the medical records could not be retrieved for 15 patients, leaving 694 for further analyses. Of these, 444 had a confirmed brain abscess and 250 had another proven diagnosis, including 47 cases of intracranial empyema. The overall PPV was 64% (95% CI: 60–68) ranging from 24% to 96% among the different codes evaluated. By including only patients with either 1) both a diagnosis and surgical procedure code for brain abscess or 2) patients admitted to hospital with certain primary diagnosis codes (DG060[C,E,F] or DG079B) without newly diagnosed central nervous system (CNS) cancer, spondylodiscitis/intraspinal abscess, or procedure codes for evacuation of intracranial empyema, the PPV increased to 84% (95% CI 80–87) and 89% (395/444) of all confirmed cases were identified. Conclusion: The overall PPV of diagnosis codes for brain abscess in the DNPR was moderate. However, by exclusion of newly diagnosed CNS tumors, spondylodiscitis/intraspinal abscess, and intracranial empyemas, the PPV was high and therefore suitable for future registry-based studies of brain abscess. Keywords: cerebral abscess, register, PPV, intracranial abscess, epidemiology |
| first_indexed | 2024-04-12T12:20:20Z |
| format | Article |
| id | doaj.art-b24436b639ec4b92acfdfa5847b3fe11 |
| institution | Directory Open Access Journal |
| issn | 1179-1349 |
| language | English |
| last_indexed | 2024-04-12T12:20:20Z |
| publishDate | 2018-10-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical Epidemiology |
| spelling | doaj.art-b24436b639ec4b92acfdfa5847b3fe112022-12-22T03:33:19ZengDove Medical PressClinical Epidemiology1179-13492018-10-01Volume 101503150841409Positive predictive value of ICD-10 diagnosis codes for brain abscess in the Danish National Patient RegistryBodilsen JDalager-Pedersen MKjærgaard Nvan de Beek DBrouwer MCNielsen HJacob Bodilsen,1 Michael Dalager-Pedersen,1 Nicolai Kjærgaard,1 Diederik van de Beek,2 Matthijs C Brouwer,2 Henrik Nielsen,1 and the DASGIB study group 1Department of Infectious Diseases, Aalborg University Hospital, Aalborg, Denmark; 2Department of Neurology, Amsterdam Neuroscience, Academic Medical Centre, Amsterdam, The Netherlands Purpose: To evaluate the positive predictive value (PPV) of ICD-10 diagnosis codes for brain abscess in the Danish National Patient Registry (DNPR). Patients and methods: We examined medical records of all patients with a first-time diagnosis code of brain abscess in the DNPR from 2007 to 2016. Patients were categorized with either confirmed or disproved brain abscess using a priori defined criteria. We computed the PPV as the proportion of confirmed diagnoses. Results: We identified 709 patients, of whom the medical records could not be retrieved for 15 patients, leaving 694 for further analyses. Of these, 444 had a confirmed brain abscess and 250 had another proven diagnosis, including 47 cases of intracranial empyema. The overall PPV was 64% (95% CI: 60–68) ranging from 24% to 96% among the different codes evaluated. By including only patients with either 1) both a diagnosis and surgical procedure code for brain abscess or 2) patients admitted to hospital with certain primary diagnosis codes (DG060[C,E,F] or DG079B) without newly diagnosed central nervous system (CNS) cancer, spondylodiscitis/intraspinal abscess, or procedure codes for evacuation of intracranial empyema, the PPV increased to 84% (95% CI 80–87) and 89% (395/444) of all confirmed cases were identified. Conclusion: The overall PPV of diagnosis codes for brain abscess in the DNPR was moderate. However, by exclusion of newly diagnosed CNS tumors, spondylodiscitis/intraspinal abscess, and intracranial empyemas, the PPV was high and therefore suitable for future registry-based studies of brain abscess. Keywords: cerebral abscess, register, PPV, intracranial abscess, epidemiologyhttps://www.dovepress.com/positive-predictive-value-of-icd-10-diagnosis-codes-for-brain-abscess--peer-reviewed-article-CLEPBrain abscessdiagnosis codesICD-10positive predictive valuevalidationepidemiology |
| spellingShingle | Bodilsen J Dalager-Pedersen M Kjærgaard N van de Beek D Brouwer MC Nielsen H Positive predictive value of ICD-10 diagnosis codes for brain abscess in the Danish National Patient Registry Clinical Epidemiology Brain abscess diagnosis codes ICD-10 positive predictive value validation epidemiology |
| title | Positive predictive value of ICD-10 diagnosis codes for brain abscess in the Danish National Patient Registry |
| title_full | Positive predictive value of ICD-10 diagnosis codes for brain abscess in the Danish National Patient Registry |
| title_fullStr | Positive predictive value of ICD-10 diagnosis codes for brain abscess in the Danish National Patient Registry |
| title_full_unstemmed | Positive predictive value of ICD-10 diagnosis codes for brain abscess in the Danish National Patient Registry |
| title_short | Positive predictive value of ICD-10 diagnosis codes for brain abscess in the Danish National Patient Registry |
| title_sort | positive predictive value of icd 10 diagnosis codes for brain abscess in the danish national patient registry |
| topic | Brain abscess diagnosis codes ICD-10 positive predictive value validation epidemiology |
| url | https://www.dovepress.com/positive-predictive-value-of-icd-10-diagnosis-codes-for-brain-abscess--peer-reviewed-article-CLEP |
| work_keys_str_mv | AT bodilsenj positivepredictivevalueoficd10diagnosiscodesforbrainabscessinthedanishnationalpatientregistry AT dalagerpedersenm positivepredictivevalueoficd10diagnosiscodesforbrainabscessinthedanishnationalpatientregistry AT kjærgaardn positivepredictivevalueoficd10diagnosiscodesforbrainabscessinthedanishnationalpatientregistry AT vandebeekd positivepredictivevalueoficd10diagnosiscodesforbrainabscessinthedanishnationalpatientregistry AT brouwermc positivepredictivevalueoficd10diagnosiscodesforbrainabscessinthedanishnationalpatientregistry AT nielsenh positivepredictivevalueoficd10diagnosiscodesforbrainabscessinthedanishnationalpatientregistry |