Sleep and wake cycles dynamically modulate hippocampal inhibitory synaptic plasticity

Sleep is an essential process that consolidates memories by modulating synapses through poorly understood mechanisms. Here, we report that GABAergic synapses in hippocampal CA1 pyramidal neurons undergo daily rhythmic alterations. Specifically, wake inhibits phasic inhibition, whereas it promotes to...

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Bibliographic Details
Main Authors: Kunwei Wu, Wenyan Han, Wei Lu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-11-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9624398/?tool=EBI