Juvenile systemic lupus erythematosus with primary neuropsychiatric presentation
Systemic lupus erythematosus (SLE) is an autoimmune disease-causing inflammatory tissue damage with multiple organ involvement. We report a 12-year-old girl who presented with 6-month history of high-grade intermittent fever and weight loss, psychiatric symptoms beginning 10 days before admission, a...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Archives of Medicine and Health Sciences |
| Subjects: | |
| Online Access: | http://www.amhsjournal.org/article.asp?issn=2321-4848;year=2023;volume=11;issue=1;spage=145;epage=147;aulast=Kulkarni |
| _version_ | 1827896306155126784 |
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| author | Rajesh Kulkarni Rhea Singh Himanshu Gohatre Sabahat Ahmed Palash Sangai Deepali Ambike |
| author_facet | Rajesh Kulkarni Rhea Singh Himanshu Gohatre Sabahat Ahmed Palash Sangai Deepali Ambike |
| author_sort | Rajesh Kulkarni |
| collection | DOAJ |
| description | Systemic lupus erythematosus (SLE) is an autoimmune disease-causing inflammatory tissue damage with multiple organ involvement. We report a 12-year-old girl who presented with 6-month history of high-grade intermittent fever and weight loss, psychiatric symptoms beginning 10 days before admission, and generalized tonic–clonic seizure 4 days before admission to our hospital. Investigation excluded infectious etiology. Immunological workup revealed high titer of antinuclear and anti-double-stranded DNA antibodies. She was treated with steroids and azathioprine and responded well to treatment. It is important to have a very high index of suspicion for the diagnosis of SLE for early diagnosis, treatment, and meticulous monitoring. |
| first_indexed | 2024-03-12T22:33:49Z |
| format | Article |
| id | doaj.art-b24b2697b91b4e4cae09ad4ff2aab9c9 |
| institution | Directory Open Access Journal |
| issn | 2321-4848 |
| language | English |
| last_indexed | 2024-03-12T22:33:49Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Archives of Medicine and Health Sciences |
| spelling | doaj.art-b24b2697b91b4e4cae09ad4ff2aab9c92023-07-21T14:21:31ZengWolters Kluwer Medknow PublicationsArchives of Medicine and Health Sciences2321-48482023-01-0111114514710.4103/amhs.amhs_24_23Juvenile systemic lupus erythematosus with primary neuropsychiatric presentationRajesh KulkarniRhea SinghHimanshu GohatreSabahat AhmedPalash SangaiDeepali AmbikeSystemic lupus erythematosus (SLE) is an autoimmune disease-causing inflammatory tissue damage with multiple organ involvement. We report a 12-year-old girl who presented with 6-month history of high-grade intermittent fever and weight loss, psychiatric symptoms beginning 10 days before admission, and generalized tonic–clonic seizure 4 days before admission to our hospital. Investigation excluded infectious etiology. Immunological workup revealed high titer of antinuclear and anti-double-stranded DNA antibodies. She was treated with steroids and azathioprine and responded well to treatment. It is important to have a very high index of suspicion for the diagnosis of SLE for early diagnosis, treatment, and meticulous monitoring.http://www.amhsjournal.org/article.asp?issn=2321-4848;year=2023;volume=11;issue=1;spage=145;epage=147;aulast=Kulkarnicentral nervous systemchildhood-onset systemic lupus erythematosusneuropsychiatric systemic lupus erythematosusseizure |
| spellingShingle | Rajesh Kulkarni Rhea Singh Himanshu Gohatre Sabahat Ahmed Palash Sangai Deepali Ambike Juvenile systemic lupus erythematosus with primary neuropsychiatric presentation Archives of Medicine and Health Sciences central nervous system childhood-onset systemic lupus erythematosus neuropsychiatric systemic lupus erythematosus seizure |
| title | Juvenile systemic lupus erythematosus with primary neuropsychiatric presentation |
| title_full | Juvenile systemic lupus erythematosus with primary neuropsychiatric presentation |
| title_fullStr | Juvenile systemic lupus erythematosus with primary neuropsychiatric presentation |
| title_full_unstemmed | Juvenile systemic lupus erythematosus with primary neuropsychiatric presentation |
| title_short | Juvenile systemic lupus erythematosus with primary neuropsychiatric presentation |
| title_sort | juvenile systemic lupus erythematosus with primary neuropsychiatric presentation |
| topic | central nervous system childhood-onset systemic lupus erythematosus neuropsychiatric systemic lupus erythematosus seizure |
| url | http://www.amhsjournal.org/article.asp?issn=2321-4848;year=2023;volume=11;issue=1;spage=145;epage=147;aulast=Kulkarni |
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