Association between prenatal or postpartum exposure to tobacco smoking and allergic rhinitis in the offspring: An updated meta-analysis of nine cohort studies
Introduction Previous studies have suggested an association between tobacco smoke exposure and allergic rhinitis. This study aimed to investigate if prenatal or postpartum smoke exposure will increase the risk of allergic rhinitis in offspring. Methods PubMed, EMBASE, and the Cochrane library were...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
European Publishing
2022-04-01
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| Series: | Tobacco Induced Diseases |
| Subjects: | |
| Online Access: | http://www.tobaccoinduceddiseases.org/Association-between-prenatal-or-postpartum-exposure-to-ntobacco-smoking-and-allergic,146905,0,2.html |
| _version_ | 1811249891357229056 |
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| author | Xinrong Li Ran Jing Shenglan Feng Hui Zhang Jianfeng Zhang Jiulin Li Wencan Cao Mingjun Jiang Yang Liu |
| author_facet | Xinrong Li Ran Jing Shenglan Feng Hui Zhang Jianfeng Zhang Jiulin Li Wencan Cao Mingjun Jiang Yang Liu |
| author_sort | Xinrong Li |
| collection | DOAJ |
| description | Introduction
Previous studies have suggested an association between tobacco
smoke exposure and allergic rhinitis. This study aimed to investigate if prenatal
or postpartum smoke exposure will increase the risk of allergic rhinitis in offspring.
Methods
PubMed, EMBASE, and the Cochrane library were searched from inception
to July 2020 for eligible studies investigating the association between smoking
exposure and allergic rhinitis. The random-effects model was adopted for the metaanalysis
to obtain the summary odds ratio (OR) with a 95% confidence interval
(CI). Subgroup analysis based on the age of children was performed. Sensitivity
analysis was carried out to check the robustness of the results. Publication bias of
included studies was assessed.
Results
This meta-analysis included nine studies, in which six studies suggested that
children exposed to prenatal smoking were more likely to develop allergic rhinitis
compared with children who were never exposed (OR=1.12; 95% CI: 1.04–1.21).
The subgroup analysis divided children those aged 10 years (OR=0.99; 95% CI: 0.82–1.20). This metaanalysis
revealed a positive relationship between postpartum smoke exposure and
the development of allergic rhinitis in offspring (OR=1.19; 95% CI: 1.03–1.39)
with marked heterogeneity. The subgroup analysis of age in the postnatal group
showed similar results in children aged >10 years (OR=1.17; 95% CI: 1.05–1.30)
and children aged <10 years (OR=1.21; 95% CI: 0.91–1.60).
Conclusions
This meta-analysis observed an association between parental smoking
exposure and allergic rhinitis in offspring. Our findings indicated that both prenatal
and postnatal smoke exposure might be risk factors for allergic rhinitis in the
offspring. |
| first_indexed | 2024-04-12T15:54:22Z |
| format | Article |
| id | doaj.art-b24ba6caa63742d39ffff75767b3ebf8 |
| institution | Directory Open Access Journal |
| issn | 1617-9625 |
| language | English |
| last_indexed | 2024-04-12T15:54:22Z |
| publishDate | 2022-04-01 |
| publisher | European Publishing |
| record_format | Article |
| series | Tobacco Induced Diseases |
| spelling | doaj.art-b24ba6caa63742d39ffff75767b3ebf82022-12-22T03:26:25ZengEuropean PublishingTobacco Induced Diseases1617-96252022-04-0120April11010.18332/tid/146905146905Association between prenatal or postpartum exposure to tobacco smoking and allergic rhinitis in the offspring: An updated meta-analysis of nine cohort studiesXinrong Li0Ran Jing1Shenglan Feng2Hui Zhang3Jianfeng Zhang4Jiulin Li5Wencan Cao6Mingjun Jiang7Yang Liu8Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaIntroduction Previous studies have suggested an association between tobacco smoke exposure and allergic rhinitis. This study aimed to investigate if prenatal or postpartum smoke exposure will increase the risk of allergic rhinitis in offspring. Methods PubMed, EMBASE, and the Cochrane library were searched from inception to July 2020 for eligible studies investigating the association between smoking exposure and allergic rhinitis. The random-effects model was adopted for the metaanalysis to obtain the summary odds ratio (OR) with a 95% confidence interval (CI). Subgroup analysis based on the age of children was performed. Sensitivity analysis was carried out to check the robustness of the results. Publication bias of included studies was assessed. Results This meta-analysis included nine studies, in which six studies suggested that children exposed to prenatal smoking were more likely to develop allergic rhinitis compared with children who were never exposed (OR=1.12; 95% CI: 1.04–1.21). The subgroup analysis divided children those aged 10 years (OR=0.99; 95% CI: 0.82–1.20). This metaanalysis revealed a positive relationship between postpartum smoke exposure and the development of allergic rhinitis in offspring (OR=1.19; 95% CI: 1.03–1.39) with marked heterogeneity. The subgroup analysis of age in the postnatal group showed similar results in children aged >10 years (OR=1.17; 95% CI: 1.05–1.30) and children aged <10 years (OR=1.21; 95% CI: 0.91–1.60). Conclusions This meta-analysis observed an association between parental smoking exposure and allergic rhinitis in offspring. Our findings indicated that both prenatal and postnatal smoke exposure might be risk factors for allergic rhinitis in the offspring.http://www.tobaccoinduceddiseases.org/Association-between-prenatal-or-postpartum-exposure-to-ntobacco-smoking-and-allergic,146905,0,2.htmltobaccoallergic rhinitisprenatalpostnatalmeta-analysis |
| spellingShingle | Xinrong Li Ran Jing Shenglan Feng Hui Zhang Jianfeng Zhang Jiulin Li Wencan Cao Mingjun Jiang Yang Liu Association between prenatal or postpartum exposure to tobacco smoking and allergic rhinitis in the offspring: An updated meta-analysis of nine cohort studies Tobacco Induced Diseases tobacco allergic rhinitis prenatal postnatal meta-analysis |
| title | Association between prenatal or postpartum exposure to
tobacco smoking and allergic rhinitis in the offspring:
An updated meta-analysis of nine cohort studies |
| title_full | Association between prenatal or postpartum exposure to
tobacco smoking and allergic rhinitis in the offspring:
An updated meta-analysis of nine cohort studies |
| title_fullStr | Association between prenatal or postpartum exposure to
tobacco smoking and allergic rhinitis in the offspring:
An updated meta-analysis of nine cohort studies |
| title_full_unstemmed | Association between prenatal or postpartum exposure to
tobacco smoking and allergic rhinitis in the offspring:
An updated meta-analysis of nine cohort studies |
| title_short | Association between prenatal or postpartum exposure to
tobacco smoking and allergic rhinitis in the offspring:
An updated meta-analysis of nine cohort studies |
| title_sort | association between prenatal or postpartum exposure to tobacco smoking and allergic rhinitis in the offspring an updated meta analysis of nine cohort studies |
| topic | tobacco allergic rhinitis prenatal postnatal meta-analysis |
| url | http://www.tobaccoinduceddiseases.org/Association-between-prenatal-or-postpartum-exposure-to-ntobacco-smoking-and-allergic,146905,0,2.html |
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