Clinical observation on superselective ophthalmic artery chemotherapy for retinoblastoma
AIM: To observe the efficacy and side reaction of superselective ophthalmic artery chemotherapy for retinoblastoma(RB).<p>METHODS: Eleven cases(11 eyes)of RB, ranging from stage A to D according to the latest International Intraocular Retinoblastoma classification, were treated with melphalan...
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| Format: | Article |
| Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2013-12-01
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| Series: | Guoji Yanke Zazhi |
| Subjects: | |
| Online Access: | http://www.ies.net.cn/cn_publish/2013/12/201312047.pdf |
| _version_ | 1818247803207417856 |
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| author | Chang-Fu Peng Jun-Jie Li Guo-Ping Duan |
| author_facet | Chang-Fu Peng Jun-Jie Li Guo-Ping Duan |
| author_sort | Chang-Fu Peng |
| collection | DOAJ |
| description | AIM: To observe the efficacy and side reaction of superselective ophthalmic artery chemotherapy for retinoblastoma(RB).<p>METHODS: Eleven cases(11 eyes)of RB, ranging from stage A to D according to the latest International Intraocular Retinoblastoma classification, were treated with melphalan infusion by the ophthalmic artery.<p>RESULTS: Such intra-arterial chemotherapy was administered for 23 times and the patients were followed up for 3-12 months. During the follow-up, 8 cases were effective with significant tumor shrinking and calcification; 2 patients progressed and received enucleation of eyeballs; 1 case was lost to follow-up. Postoperative transient nausea, vomiting and fever appeared in some cases, but serious complications were not found, such as death, stroke, myelosuppression,<i>etc</i>.<p>CONCLUSION: Among 9 cases from group A, B and C, 7 cases were effective, 1 case continued to progress and 1 case was lost to follow-up, and the effective rate was 88%. In the 2 cases of group D, 1 case was effective and the other continueed to progress, so the effective rate was 50%. |
| first_indexed | 2024-12-12T15:10:30Z |
| format | Article |
| id | doaj.art-b24f785e6d70458da5d15f31299ddf57 |
| institution | Directory Open Access Journal |
| issn | 1672-5123 |
| language | English |
| last_indexed | 2024-12-12T15:10:30Z |
| publishDate | 2013-12-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | Guoji Yanke Zazhi |
| spelling | doaj.art-b24f785e6d70458da5d15f31299ddf572022-12-22T00:20:38ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51232013-12-0113122519252110.3980/j.issn.1672-5123.2013.12.47Clinical observation on superselective ophthalmic artery chemotherapy for retinoblastomaChang-Fu PengJun-Jie LiGuo-Ping DuanAIM: To observe the efficacy and side reaction of superselective ophthalmic artery chemotherapy for retinoblastoma(RB).<p>METHODS: Eleven cases(11 eyes)of RB, ranging from stage A to D according to the latest International Intraocular Retinoblastoma classification, were treated with melphalan infusion by the ophthalmic artery.<p>RESULTS: Such intra-arterial chemotherapy was administered for 23 times and the patients were followed up for 3-12 months. During the follow-up, 8 cases were effective with significant tumor shrinking and calcification; 2 patients progressed and received enucleation of eyeballs; 1 case was lost to follow-up. Postoperative transient nausea, vomiting and fever appeared in some cases, but serious complications were not found, such as death, stroke, myelosuppression,<i>etc</i>.<p>CONCLUSION: Among 9 cases from group A, B and C, 7 cases were effective, 1 case continued to progress and 1 case was lost to follow-up, and the effective rate was 88%. In the 2 cases of group D, 1 case was effective and the other continueed to progress, so the effective rate was 50%.http://www.ies.net.cn/cn_publish/2013/12/201312047.pdfartery chemotherapymelphalanretino- blastoma |
| spellingShingle | Chang-Fu Peng Jun-Jie Li Guo-Ping Duan Clinical observation on superselective ophthalmic artery chemotherapy for retinoblastoma Guoji Yanke Zazhi artery chemotherapy melphalan retino- blastoma |
| title | Clinical observation on superselective ophthalmic artery chemotherapy for retinoblastoma |
| title_full | Clinical observation on superselective ophthalmic artery chemotherapy for retinoblastoma |
| title_fullStr | Clinical observation on superselective ophthalmic artery chemotherapy for retinoblastoma |
| title_full_unstemmed | Clinical observation on superselective ophthalmic artery chemotherapy for retinoblastoma |
| title_short | Clinical observation on superselective ophthalmic artery chemotherapy for retinoblastoma |
| title_sort | clinical observation on superselective ophthalmic artery chemotherapy for retinoblastoma |
| topic | artery chemotherapy melphalan retino- blastoma |
| url | http://www.ies.net.cn/cn_publish/2013/12/201312047.pdf |
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