Dissecting Immunosuppressive Cell Communication Patterns Reveals JunB Proto-Oncogene (JUNB) Shaping a Non-Inflamed Tumor Microenvironment

Dissecting Immunosuppressive Cell Communication Patterns Reveals JunB Proto-Oncogene (JUNB) Shaping a Non-Inflamed Tumor Microenvironment

Background: Immunosuppressive cell interactions are responsible for tumor progression and metastasis, as well as anti-tumor immune dysfunction. However, the communication pattern remains unclear.Methods: We first integrated two single-cell RNA-seq datasets (GSE72056 and GSE103322) of different tumor...

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Bibliographic Details
Main Authors: Hualin Chen, Gang Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Genetics
Subjects:
JunB
immunosuppressive
tumor microenvironment
cell communication
ScRNA-seq
molecular subtype
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.883583/full

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https://www.frontiersin.org/articles/10.3389/fgene.2022.883583/full

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