Outcomes of pediatric cataract surgery with triamcinolone-assisted vitrectomy

Background/Purpose: To evaluate outcomes in pediatric patients undergoing lensectomy, posterior capsulotomy, and triamcinolone-assisted vitrectomy for congenital cataract. Methods: This retrospective study included 34 patients younger than 72 months who underwent lensectomy, posterior capsulotomy, a...

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Main Authors: Tzu-Hsun Tsai, Chia-Ying Tsai, Jehn-Yu Huang, Fung-Rong Hu
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Journal of the Formosan Medical Association
Online Access:http://www.sciencedirect.com/science/article/pii/S0929664616304016
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author Tzu-Hsun Tsai
Chia-Ying Tsai
Jehn-Yu Huang
Fung-Rong Hu
author_facet Tzu-Hsun Tsai
Chia-Ying Tsai
Jehn-Yu Huang
Fung-Rong Hu
author_sort Tzu-Hsun Tsai
collection DOAJ
description Background/Purpose: To evaluate outcomes in pediatric patients undergoing lensectomy, posterior capsulotomy, and triamcinolone-assisted vitrectomy for congenital cataract. Methods: This retrospective study included 34 patients younger than 72 months who underwent lensectomy, posterior capsulotomy, and triamcinolone-assisted vitrectomy with or without intraocular lens (IOL) implantation for cataract at the National Taiwan University Hospital from July 2006 to December 2012. Results: Fifty-one eyes from 34 patients with cataract (unilateral in 17 patients, bilateral in 17 patients) were included. The mean age at surgery was 26.74 months (range: 2â72 months). The mean postoperative follow-up was 27.8 months (range: 6â72 months). Primary IOL implantation was performed in 25 eyes, 21 of which had the IOL implanted in the capsular bag. Fifty eyes had a central round pupil. The median logarithm of the minimum angle of resolution visual acuity was 0.3 in patients with unilateral cataract and 0.1 in those with bilateral cataract. Three eyes (5.9%) developed visual axis opacification (VAO) and required further surgery. Univariate analysis using Fisherâs exact test indicated that surgery in the first 12 months of life was significantly associated with development of VAO (p=0.047). The incidence of postoperative VAO was approximately 15.8% in this age group. Conclusion: Triamcinolone-assisted vitrectomy can be used in pediatric cataract surgery without serious long-term adverse effects. While the incidence of VAO is low, it appears unavoidable in approximately one-sixth of patients who undergo surgery before 12 months of age. Keywords: anterior vitrectomy, pediatric cataract, triamcinolone acetonide
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spelling doaj.art-b255275b899444b499b478771319a2c62022-12-22T01:37:57ZengElsevierJournal of the Formosan Medical Association0929-66462017-12-0111612940945Outcomes of pediatric cataract surgery with triamcinolone-assisted vitrectomyTzu-Hsun Tsai0Chia-Ying Tsai1Jehn-Yu Huang2Fung-Rong Hu3Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan, Republic of China; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan, Republic of ChinaDepartment of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan, Republic of ChinaDepartment of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan, Republic of China; Department of Ophthalmology, National Taiwan University College of Medicine, Taipei, Taiwan, Republic of ChinaDepartment of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan, Republic of China; Department of Ophthalmology, National Taiwan University College of Medicine, Taipei, Taiwan, Republic of China; Corresponding author. Department of Ophthalmology, National Taiwan University Hospital, 12F, No. 7, Zhongshan South Road, Taipei City, 100, Taiwan, Republic of China.Background/Purpose: To evaluate outcomes in pediatric patients undergoing lensectomy, posterior capsulotomy, and triamcinolone-assisted vitrectomy for congenital cataract. Methods: This retrospective study included 34 patients younger than 72 months who underwent lensectomy, posterior capsulotomy, and triamcinolone-assisted vitrectomy with or without intraocular lens (IOL) implantation for cataract at the National Taiwan University Hospital from July 2006 to December 2012. Results: Fifty-one eyes from 34 patients with cataract (unilateral in 17 patients, bilateral in 17 patients) were included. The mean age at surgery was 26.74 months (range: 2â72 months). The mean postoperative follow-up was 27.8 months (range: 6â72 months). Primary IOL implantation was performed in 25 eyes, 21 of which had the IOL implanted in the capsular bag. Fifty eyes had a central round pupil. The median logarithm of the minimum angle of resolution visual acuity was 0.3 in patients with unilateral cataract and 0.1 in those with bilateral cataract. Three eyes (5.9%) developed visual axis opacification (VAO) and required further surgery. Univariate analysis using Fisherâs exact test indicated that surgery in the first 12 months of life was significantly associated with development of VAO (p=0.047). The incidence of postoperative VAO was approximately 15.8% in this age group. Conclusion: Triamcinolone-assisted vitrectomy can be used in pediatric cataract surgery without serious long-term adverse effects. While the incidence of VAO is low, it appears unavoidable in approximately one-sixth of patients who undergo surgery before 12 months of age. Keywords: anterior vitrectomy, pediatric cataract, triamcinolone acetonidehttp://www.sciencedirect.com/science/article/pii/S0929664616304016
spellingShingle Tzu-Hsun Tsai
Chia-Ying Tsai
Jehn-Yu Huang
Fung-Rong Hu
Outcomes of pediatric cataract surgery with triamcinolone-assisted vitrectomy
Journal of the Formosan Medical Association
title Outcomes of pediatric cataract surgery with triamcinolone-assisted vitrectomy
title_full Outcomes of pediatric cataract surgery with triamcinolone-assisted vitrectomy
title_fullStr Outcomes of pediatric cataract surgery with triamcinolone-assisted vitrectomy
title_full_unstemmed Outcomes of pediatric cataract surgery with triamcinolone-assisted vitrectomy
title_short Outcomes of pediatric cataract surgery with triamcinolone-assisted vitrectomy
title_sort outcomes of pediatric cataract surgery with triamcinolone assisted vitrectomy
url http://www.sciencedirect.com/science/article/pii/S0929664616304016
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