Leprosy and American cutaneous leishmaniasis coinfection

Abstract: Brazil is a country with a high prevalence of infectious diseases such as leprosy and leishmaniasis. However, coinfection of these diseases is still poorly understood. We report a case of a patient who presented with lepromatous leprosy and cutaneous-mucosal leishmaniasis at the same perio...

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Main Authors: Larissa Mondadori Mercadante, Marcel Alex Soares dos Santos, Elisangela Samartin Pegas, Bogdana Victória Kadunc
Format: Article
Language:English
Published: Sociedade Brasileira de Dermatologia 2018-02-01
Series:Anais Brasileiros de Dermatologia
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962018000100123&tlng=en
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author Larissa Mondadori Mercadante
Marcel Alex Soares dos Santos
Elisangela Samartin Pegas
Bogdana Victória Kadunc
author_facet Larissa Mondadori Mercadante
Marcel Alex Soares dos Santos
Elisangela Samartin Pegas
Bogdana Victória Kadunc
author_sort Larissa Mondadori Mercadante
collection DOAJ
description Abstract: Brazil is a country with a high prevalence of infectious diseases such as leprosy and leishmaniasis. However, coinfection of these diseases is still poorly understood. We report a case of a patient who presented with lepromatous leprosy and cutaneous-mucosal leishmaniasis at the same period. After clinical, laboratory, and histopathological diagnosis, the treatment was introduced and the patient showed important clinical improvement. He was followed in our outpatient clinic. Both pathologies play an important role in the immune system. Depending on the immune response profile of the host, diseases may present themselves in different ways. In this case, the patient showed a divergent immune response for each disease. We hypothesized that this response is specific for each pathogen.
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spelling doaj.art-b256bac72b44432281b9ff3b69d6fa852022-12-21T19:36:35ZengSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia0365-05962018-02-0193112312510.1590/abd1806-4841.20186698Leprosy and American cutaneous leishmaniasis coinfectionLarissa Mondadori MercadanteMarcel Alex Soares dos SantosElisangela Samartin PegasBogdana Victória KaduncAbstract: Brazil is a country with a high prevalence of infectious diseases such as leprosy and leishmaniasis. However, coinfection of these diseases is still poorly understood. We report a case of a patient who presented with lepromatous leprosy and cutaneous-mucosal leishmaniasis at the same period. After clinical, laboratory, and histopathological diagnosis, the treatment was introduced and the patient showed important clinical improvement. He was followed in our outpatient clinic. Both pathologies play an important role in the immune system. Depending on the immune response profile of the host, diseases may present themselves in different ways. In this case, the patient showed a divergent immune response for each disease. We hypothesized that this response is specific for each pathogen.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962018000100123&tlng=enLeishmaniasisLeprosyImmunity
spellingShingle Larissa Mondadori Mercadante
Marcel Alex Soares dos Santos
Elisangela Samartin Pegas
Bogdana Victória Kadunc
Leprosy and American cutaneous leishmaniasis coinfection
Anais Brasileiros de Dermatologia
Leishmaniasis
Leprosy
Immunity
title Leprosy and American cutaneous leishmaniasis coinfection
title_full Leprosy and American cutaneous leishmaniasis coinfection
title_fullStr Leprosy and American cutaneous leishmaniasis coinfection
title_full_unstemmed Leprosy and American cutaneous leishmaniasis coinfection
title_short Leprosy and American cutaneous leishmaniasis coinfection
title_sort leprosy and american cutaneous leishmaniasis coinfection
topic Leishmaniasis
Leprosy
Immunity
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962018000100123&tlng=en
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