Advances in the delivery of bioactive compounds using starch-based nanogels: Formation mechanism, contemporary challenges, and prospects
Despite the widespread interest in starch-based nanogels due to their excellent swelling capacity and biocompatibility, there is a lack of in-depth analysis in the existing literature on the effects of their preparation methods, internal structure, and physicochemical properties on the release, rete...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-06-01
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| Series: | Journal of Agriculture and Food Research |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666154324001790 |
| _version_ | 1827238452088799232 |
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| author | Zhaoxing Yang Fang Xie Jie Cai |
| author_facet | Zhaoxing Yang Fang Xie Jie Cai |
| author_sort | Zhaoxing Yang |
| collection | DOAJ |
| description | Despite the widespread interest in starch-based nanogels due to their excellent swelling capacity and biocompatibility, there is a lack of in-depth analysis in the existing literature on the effects of their preparation methods, internal structure, and physicochemical properties on the release, retention, and protection of bioactive when used as delivery systems. In addition, there is a lack of systematic integration and discussion on the theoretical basis of how to design starch-based nanogels with specific structures and functions and the specific functions of these nanogels in oral-gastrointestinal digestive delivery systems. In this review, the preparation methods, characterization, and functions of starch-based nanogels are discussed in association with the delivery process to further understand the influence that the preparation method, as well as the structural and physicochemical characteristics have on the construction of the nanogel. This review aims to offer a theoretical foundation for designing starch-based nanogels with specific structures and functions. Summarizing functions of starch-based nanogels in an oral–gastrointestinal digestive delivery system can lay the foundation for the further development of starch-based nanogels as delivery systems. Furthermore, it can also deliver valuable insights and direct the development of healthy food items in an industrial setting. |
| first_indexed | 2024-04-24T10:03:24Z |
| format | Article |
| id | doaj.art-b258be4f023b4255a332adb4f0ef34a4 |
| institution | Directory Open Access Journal |
| issn | 2666-1543 |
| language | English |
| last_indexed | 2025-03-21T20:53:01Z |
| publishDate | 2024-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Agriculture and Food Research |
| spelling | doaj.art-b258be4f023b4255a332adb4f0ef34a42024-05-31T05:44:08ZengElsevierJournal of Agriculture and Food Research2666-15432024-06-0116101142Advances in the delivery of bioactive compounds using starch-based nanogels: Formation mechanism, contemporary challenges, and prospectsZhaoxing Yang0Fang Xie1Jie Cai2School of Modern Industry for Selenium Science and Engineering, Wuhan Polytechnic University, Wuhan, 430023, PR ChinaSchool of Modern Industry for Selenium Science and Engineering, Wuhan Polytechnic University, Wuhan, 430023, PR ChinaSchool of Modern Industry for Selenium Science and Engineering, Wuhan Polytechnic University, Wuhan, 430023, PR China; Key Laboratory for Deep Processing of Major Grain and Oil, Ministry of Education, Hubei Key Laboratory for Processing and Transformation of Agricultural Products, Wuhan Polytechnic University, Wuhan, 430023, PR China; Corresponding author. School of Modern Industry for Selenium Science and Engineering, Wuhan Polytechnic University, Wuhan, 430023, PR China.Despite the widespread interest in starch-based nanogels due to their excellent swelling capacity and biocompatibility, there is a lack of in-depth analysis in the existing literature on the effects of their preparation methods, internal structure, and physicochemical properties on the release, retention, and protection of bioactive when used as delivery systems. In addition, there is a lack of systematic integration and discussion on the theoretical basis of how to design starch-based nanogels with specific structures and functions and the specific functions of these nanogels in oral-gastrointestinal digestive delivery systems. In this review, the preparation methods, characterization, and functions of starch-based nanogels are discussed in association with the delivery process to further understand the influence that the preparation method, as well as the structural and physicochemical characteristics have on the construction of the nanogel. This review aims to offer a theoretical foundation for designing starch-based nanogels with specific structures and functions. Summarizing functions of starch-based nanogels in an oral–gastrointestinal digestive delivery system can lay the foundation for the further development of starch-based nanogels as delivery systems. Furthermore, it can also deliver valuable insights and direct the development of healthy food items in an industrial setting.http://www.sciencedirect.com/science/article/pii/S2666154324001790NanomaterialBioactive substancesControlled delivery/release systemBioavailability |
| spellingShingle | Zhaoxing Yang Fang Xie Jie Cai Advances in the delivery of bioactive compounds using starch-based nanogels: Formation mechanism, contemporary challenges, and prospects Journal of Agriculture and Food Research Nanomaterial Bioactive substances Controlled delivery/release system Bioavailability |
| title | Advances in the delivery of bioactive compounds using starch-based nanogels: Formation mechanism, contemporary challenges, and prospects |
| title_full | Advances in the delivery of bioactive compounds using starch-based nanogels: Formation mechanism, contemporary challenges, and prospects |
| title_fullStr | Advances in the delivery of bioactive compounds using starch-based nanogels: Formation mechanism, contemporary challenges, and prospects |
| title_full_unstemmed | Advances in the delivery of bioactive compounds using starch-based nanogels: Formation mechanism, contemporary challenges, and prospects |
| title_short | Advances in the delivery of bioactive compounds using starch-based nanogels: Formation mechanism, contemporary challenges, and prospects |
| title_sort | advances in the delivery of bioactive compounds using starch based nanogels formation mechanism contemporary challenges and prospects |
| topic | Nanomaterial Bioactive substances Controlled delivery/release system Bioavailability |
| url | http://www.sciencedirect.com/science/article/pii/S2666154324001790 |
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