Drug Trafficking into Macrophages via the Endocytotic Receptor CD163

Drug Trafficking into Macrophages via the Endocytotic Receptor CD163

In inflammatory diseases, macrophages are a main producer of a range of cytokines regulating the inflammatory state. This also includes inflammation induced by tumor growth, which recruits so-called tumor-associated macrophages supporting tumor growth. Macrophages are therefore relevant targets for...

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Bibliographic Details
Main Authors: Jonas Heilskov Graversen, Søren Kragh Moestrup
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:Membranes
Subjects:
macrophage
CD163
dexamethasone
antibody drug conjugate
targeting
inflammation
internalization
Online Access:http://www.mdpi.com/2077-0375/5/2/228

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