Clinical laboratory diagnostics of immunosuppressants: One laboratory’s journey

Laboratory support for the organ transplant patient is the provision of the best testing technology for a specific and accurate determination of immunosuppressive drug level. This translates to better management with the therapeutic cocktail of immunosuppressive drugs used with a lesser incidence of...

Full description

Bibliographic Details
Main Authors: Wai Yoong Ng, Chin Pin Yeo
Format: Article
Language:English
Published: SAGE Publishing 2015-12-01
Series:Proceedings of Singapore Healthcare
Online Access:https://doi.org/10.1177/2010105815611807
_version_ 1811331285522579456
author Wai Yoong Ng
Chin Pin Yeo
author_facet Wai Yoong Ng
Chin Pin Yeo
author_sort Wai Yoong Ng
collection DOAJ
description Laboratory support for the organ transplant patient is the provision of the best testing technology for a specific and accurate determination of immunosuppressive drug level. This translates to better management with the therapeutic cocktail of immunosuppressive drugs used with a lesser incidence of organ rejection and side effects. Over the years, development of automated immunoassay/chemistry test platforms with standardization of test protocols has demonstrated great improvements. The present clinical laboratory services with tandem mass spectrometry in our hospital present more precise and specific therapeutic drug monitoring so necessary still for the patient. This article follows the evolving testing technologies over the years for immunosuppressive drug monitoring following the organ transplants programme (renal in general) in Singapore General Hospital.
first_indexed 2024-04-13T16:18:28Z
format Article
id doaj.art-b25c200827024a30a376fdb39b70fc1d
institution Directory Open Access Journal
issn 2010-1058
2059-2329
language English
last_indexed 2024-04-13T16:18:28Z
publishDate 2015-12-01
publisher SAGE Publishing
record_format Article
series Proceedings of Singapore Healthcare
spelling doaj.art-b25c200827024a30a376fdb39b70fc1d2022-12-22T02:40:00ZengSAGE PublishingProceedings of Singapore Healthcare2010-10582059-23292015-12-012410.1177/2010105815611807Clinical laboratory diagnostics of immunosuppressants: One laboratory’s journeyWai Yoong NgChin Pin YeoLaboratory support for the organ transplant patient is the provision of the best testing technology for a specific and accurate determination of immunosuppressive drug level. This translates to better management with the therapeutic cocktail of immunosuppressive drugs used with a lesser incidence of organ rejection and side effects. Over the years, development of automated immunoassay/chemistry test platforms with standardization of test protocols has demonstrated great improvements. The present clinical laboratory services with tandem mass spectrometry in our hospital present more precise and specific therapeutic drug monitoring so necessary still for the patient. This article follows the evolving testing technologies over the years for immunosuppressive drug monitoring following the organ transplants programme (renal in general) in Singapore General Hospital.https://doi.org/10.1177/2010105815611807
spellingShingle Wai Yoong Ng
Chin Pin Yeo
Clinical laboratory diagnostics of immunosuppressants: One laboratory’s journey
Proceedings of Singapore Healthcare
title Clinical laboratory diagnostics of immunosuppressants: One laboratory’s journey
title_full Clinical laboratory diagnostics of immunosuppressants: One laboratory’s journey
title_fullStr Clinical laboratory diagnostics of immunosuppressants: One laboratory’s journey
title_full_unstemmed Clinical laboratory diagnostics of immunosuppressants: One laboratory’s journey
title_short Clinical laboratory diagnostics of immunosuppressants: One laboratory’s journey
title_sort clinical laboratory diagnostics of immunosuppressants one laboratory s journey
url https://doi.org/10.1177/2010105815611807
work_keys_str_mv AT waiyoongng clinicallaboratorydiagnosticsofimmunosuppressantsonelaboratorysjourney
AT chinpinyeo clinicallaboratorydiagnosticsofimmunosuppressantsonelaboratorysjourney