Human-induced pluripotent stem cells-derived retinal pigmented epithelium, a new horizon for cells-based therapies for age-related macular degeneration

Human-induced pluripotent stem cells-derived retinal pigmented epithelium, a new horizon for cells-based therapies for age-related macular degeneration

Abstract Retinal pigment epithelium (RPE) degeneration is the hallmark of age-related macular degeneration (AMD). AMD, as one of the most common causes of irreversible visual impairment worldwide, remains in need of an appropriate approach to restore retinal function. Wet AMD, which is characterized...

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Bibliographic Details
Main Authors: Samaneh Dehghan, Reza Mirshahi, Alireza Shoae-Hassani, Masood Naseripour
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Stem Cell Research & Therapy
Subjects:
Cell therapy
Age-related macular degeneration
Retinal pigmented epithelium
Induced pluripotent stem cells
Retina
Clinical trial
Online Access:https://doi.org/10.1186/s13287-022-02894-0

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