Loop-mediated isothermal amplification (LAMP) colorimetric phenol red assay for rapid identification of α0-thalassemia: Application to population screening and prenatal diagnosis.
<h4>Background</h4>Identification of α0-thalassemia (SEA and THAI deletions) is essential in preventing and controlling of severe thalassemia diseases. We have developed the LAMP colorimetric assays for the detection of these two thalassemia defects and validated them in population scree...
Main Authors: | Wittaya Jomoui, Hataichanok Srivorakun, Siriyakorn Chansai, Supan Fucharoen |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2022-01-01
|
Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0267832 |
Similar Items
-
Rapid molecular diagnostics of large deletional β0-thalassemia (3.5 kb and 45 kb) using colorimetric LAMP in various thalassemia genotypes
by: Wanicha Tepakhan, et al.
Published: (2021-11-01) -
The correlation between ineffective erythropoiesis biomarkers and development of extramedullary hematopoiesis in patients with thalassemia
by: Siriyakorn Chansai, et al.
Published: (2022-06-01) -
Thalassemia and erythroid transcription factor KLF1 mutations associated with borderline hemoglobin A2
in the Thai population
by: Hataichanok Srivorakun, et al.
Published: (2020-08-01) -
Diagnostic value of fetal hemoglobin Bart’s for evaluation of fetal α-thalassemia syndromes: application to prenatal characterization of fetal anemia caused by undiagnosed α-hemoglobinopathy
by: Kritsada Singha, et al.
Published: (2022-02-01) -
Molecular basis of a high Hb A2/Hb Fβ-thalassemia trait: a retrospective analysis, genotype-phenotype interaction, diagnostic implication, and identification of a novel interaction with α-globin gene triplication
by: Chayada Soontornpanawet, et al.
Published: (2023-05-01)