Targeting Mitochondrial Network Architecture in Down Syndrome and Aging

Targeting Mitochondrial Network Architecture in Down Syndrome and Aging

Mitochondria are organelles that mainly control energy conversion in the cell. In addition, they also participate in many relevant activities, such as the regulation of apoptosis and calcium levels, and other metabolic tasks, all closely linked to cell viability. Functionality of mitochondria appear...

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Bibliographic Details
Main Authors: Nunzia Mollo, Rita Cicatiello, Miriam Aurilia, Roberta Scognamiglio, Rita Genesio, Maria Charalambous, Simona Paladino, Anna Conti, Lucio Nitsch, Antonella Izzo
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
Down syndrome
aging
mitochondrial dynamics
mitochondrial network
mitochondrial function
PGC-1α/PPARGC1A
Online Access:https://www.mdpi.com/1422-0067/21/9/3134

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