The Anti-Leukemia Effect of Ascorbic Acid: From the Pro-Oxidant Potential to the Epigenetic Role in Acute Myeloid Leukemia

The Anti-Leukemia Effect of Ascorbic Acid: From the Pro-Oxidant Potential to the Epigenetic Role in Acute Myeloid Leukemia

Data derived from high-throughput sequencing technologies have allowed a deeper understanding of the molecular landscape of Acute Myeloid Leukemia (AML), paving the way for the development of novel therapeutic options, with a higher efficacy and a lower toxicity than conventional chemotherapy. In th...

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Bibliographic Details
Main Authors: S. Travaglini, C. Gurnari, S. Antonelli, G. Silvestrini, N. I. Noguera, T. Ottone, M. T. Voso
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
acute myeloid leukemia
ascorbic acid
epigenetic regulation
oxidative stress
vitamin C
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.930205/full

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