Influence of C-terminal truncation of murine Serum amyloid A on fibril structure

Influence of C-terminal truncation of murine Serum amyloid A on fibril structure

Abstract Amyloid A (AA) amyloidosis is a systemic protein misfolding disease affecting humans and other vertebrates. While the protein precursor in humans and mice is the acute-phase reactant serum amyloid A (SAA) 1.1, the deposited fibrils consist mainly of C-terminally truncated SAA fragments, ter...

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Bibliographic Details
Main Authors:	Matthies Rennegarbe, Inga Lenter, Angelika Schierhorn, Romy Sawilla, Christian Haupt
Format:	Article
Language:	English
Published:	Nature Portfolio 2017-07-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-017-06419-1

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