EIF4A3-induced circBRWD3 promotes tumorigenesis of breast cancer through miR-142-3p_miR-142-5p/RAC1/PAK1 signaling

EIF4A3-induced circBRWD3 promotes tumorigenesis of breast cancer through miR-142-3p_miR-142-5p/RAC1/PAK1 signaling

Abstract CircBRWD3 is a newly discovered circRNA, and its potential function has not been probed. Here, we aimed to molecularly dissect the role of circBRWD3 in the tumorigenesis and progression of breast cancer (BC). qRT-PCR analysis revealed that circBRWD3 expression was dramatically upregulated i...

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Bibliographic Details
Main Authors:	Xianguo Meng, Wei Li, Ziqi Meng, Yan Li
Format:	Article
Language:	English
Published:	BMC 2022-11-01
Series:	BMC Cancer
Subjects:	Breast cancer EIF4A3 CircBRWD3 MiR-142-3p MiR-142-5p RAC1-PAK1 signaling
Online Access:	https://doi.org/10.1186/s12885-022-10200-7

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