Case Report: First case of HIV, hepatitis B, hepatitis C, and Vibrio vulnificus coinfection
Our patient, a 48-year-old man from Guangdong’s coastal region, worked selling and processing oysters and other seafood. He started experiencing swelling and pain in his left knee on October 4, 2022, and they got worse over time. The findings of mNGS test showed Vibrio vulnificus infection. The pati...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-12-01
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| Series: | Frontiers in Cellular and Infection Microbiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fcimb.2023.1290636/full |
| _version_ | 1797397500394471424 |
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| author | Huimin Zeng Jialong Guan Chudan Liang Chudan Liang Yulong Wang Yulong Wang Lizhi Feng Han Zhao Linjin Fan Xiaofeng Yang Xiaofeng Yang Nenglang Pan Zequn Wang Zequn Wang Haolan He Zhimin Chen Jun Qian Jun Qian Yueping Li Linna Liu |
| author_facet | Huimin Zeng Jialong Guan Chudan Liang Chudan Liang Yulong Wang Yulong Wang Lizhi Feng Han Zhao Linjin Fan Xiaofeng Yang Xiaofeng Yang Nenglang Pan Zequn Wang Zequn Wang Haolan He Zhimin Chen Jun Qian Jun Qian Yueping Li Linna Liu |
| author_sort | Huimin Zeng |
| collection | DOAJ |
| description | Our patient, a 48-year-old man from Guangdong’s coastal region, worked selling and processing oysters and other seafood. He started experiencing swelling and pain in his left knee on October 4, 2022, and they got worse over time. The findings of mNGS test showed Vibrio vulnificus infection. The patient had AIDS, hepatitis A and hepatitis B concurrently. He was admitted to the hospital’s intensive care unit (ICU) for treatment as his symptoms worsened. We refrained from performing an amputation because the family members expressed a desire to keep the limb. The limb was managed with regular dressing changes, thorough debridement, wound closure, ongoing VSD drainage, and local antibiotic irrigation. The patient’s organ function eventually returned to normal, and the systemic infection got better. On November 1, the wound’s new granulation tissue had grown well and had gradually crept to cover 80% of the wound. The tissue’s blood flow had also improved, indicating a trend of growth and healing. |
| first_indexed | 2024-03-09T01:10:53Z |
| format | Article |
| id | doaj.art-b27c531d8c324207ae402e78bd3804d3 |
| institution | Directory Open Access Journal |
| issn | 2235-2988 |
| language | English |
| last_indexed | 2024-03-09T01:10:53Z |
| publishDate | 2023-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cellular and Infection Microbiology |
| spelling | doaj.art-b27c531d8c324207ae402e78bd3804d32023-12-11T05:35:49ZengFrontiers Media S.A.Frontiers in Cellular and Infection Microbiology2235-29882023-12-011310.3389/fcimb.2023.12906361290636Case Report: First case of HIV, hepatitis B, hepatitis C, and Vibrio vulnificus coinfectionHuimin Zeng0Jialong Guan1Chudan Liang2Chudan Liang3Yulong Wang4Yulong Wang5Lizhi Feng6Han Zhao7Linjin Fan8Xiaofeng Yang9Xiaofeng Yang10Nenglang Pan11Zequn Wang12Zequn Wang13Haolan He14Zhimin Chen15Jun Qian16Jun Qian17Yueping Li18Linna Liu19Institute of Infectious Diseases, Guangzhou Eighth People’s Hospital, Guangzhou Medical University, Guangzhou, ChinaInstitute of Infectious Diseases, Guangzhou Eighth People’s Hospital, Guangzhou Medical University, Guangzhou, ChinaZhongshan School of Medicine, Sun Yat-sen University, Guangzhou, ChinaKey Laboratory of Tropical Disease Control (Sun Yat-sen University), Ministry of Education, Guangzhou, ChinaZhongshan School of Medicine, Sun Yat-sen University, Guangzhou, ChinaKey Laboratory of Tropical Disease Control (Sun Yat-sen University), Ministry of Education, Guangzhou, ChinaInstitute of Infectious Diseases, Guangzhou Eighth People’s Hospital, Guangzhou Medical University, Guangzhou, ChinaInstitute of Infectious Diseases, Guangzhou Eighth People’s Hospital, Guangzhou Medical University, Guangzhou, ChinaInstitute of Infectious Diseases, Guangzhou Eighth People’s Hospital, Guangzhou Medical University, Guangzhou, ChinaZhongshan School of Medicine, Sun Yat-sen University, Guangzhou, ChinaKey Laboratory of Tropical Disease Control (Sun Yat-sen University), Ministry of Education, Guangzhou, ChinaInstitute of Infectious Diseases, Guangzhou Eighth People’s Hospital, Guangzhou Medical University, Guangzhou, ChinaZhongshan School of Medicine, Sun Yat-sen University, Guangzhou, ChinaKey Laboratory of Tropical Disease Control (Sun Yat-sen University), Ministry of Education, Guangzhou, ChinaInstitute of Infectious Diseases, Guangzhou Eighth People’s Hospital, Guangzhou Medical University, Guangzhou, ChinaInstitute of Infectious Diseases, Guangzhou Eighth People’s Hospital, Guangzhou Medical University, Guangzhou, ChinaZhongshan School of Medicine, Sun Yat-sen University, Guangzhou, ChinaKey Laboratory of Tropical Disease Control (Sun Yat-sen University), Ministry of Education, Guangzhou, ChinaInstitute of Infectious Diseases, Guangzhou Eighth People’s Hospital, Guangzhou Medical University, Guangzhou, ChinaInstitute of Infectious Diseases, Guangzhou Eighth People’s Hospital, Guangzhou Medical University, Guangzhou, ChinaOur patient, a 48-year-old man from Guangdong’s coastal region, worked selling and processing oysters and other seafood. He started experiencing swelling and pain in his left knee on October 4, 2022, and they got worse over time. The findings of mNGS test showed Vibrio vulnificus infection. The patient had AIDS, hepatitis A and hepatitis B concurrently. He was admitted to the hospital’s intensive care unit (ICU) for treatment as his symptoms worsened. We refrained from performing an amputation because the family members expressed a desire to keep the limb. The limb was managed with regular dressing changes, thorough debridement, wound closure, ongoing VSD drainage, and local antibiotic irrigation. The patient’s organ function eventually returned to normal, and the systemic infection got better. On November 1, the wound’s new granulation tissue had grown well and had gradually crept to cover 80% of the wound. The tissue’s blood flow had also improved, indicating a trend of growth and healing.https://www.frontiersin.org/articles/10.3389/fcimb.2023.1290636/fullHIVhepatitis Bhepatitis CVibrio vulnificushamster models |
| spellingShingle | Huimin Zeng Jialong Guan Chudan Liang Chudan Liang Yulong Wang Yulong Wang Lizhi Feng Han Zhao Linjin Fan Xiaofeng Yang Xiaofeng Yang Nenglang Pan Zequn Wang Zequn Wang Haolan He Zhimin Chen Jun Qian Jun Qian Yueping Li Linna Liu Case Report: First case of HIV, hepatitis B, hepatitis C, and Vibrio vulnificus coinfection Frontiers in Cellular and Infection Microbiology HIV hepatitis B hepatitis C Vibrio vulnificus hamster models |
| title | Case Report: First case of HIV, hepatitis B, hepatitis C, and Vibrio vulnificus coinfection |
| title_full | Case Report: First case of HIV, hepatitis B, hepatitis C, and Vibrio vulnificus coinfection |
| title_fullStr | Case Report: First case of HIV, hepatitis B, hepatitis C, and Vibrio vulnificus coinfection |
| title_full_unstemmed | Case Report: First case of HIV, hepatitis B, hepatitis C, and Vibrio vulnificus coinfection |
| title_short | Case Report: First case of HIV, hepatitis B, hepatitis C, and Vibrio vulnificus coinfection |
| title_sort | case report first case of hiv hepatitis b hepatitis c and vibrio vulnificus coinfection |
| topic | HIV hepatitis B hepatitis C Vibrio vulnificus hamster models |
| url | https://www.frontiersin.org/articles/10.3389/fcimb.2023.1290636/full |
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