Perioperative allergy. A 3-year experience

Background: Perioperative hypersensitivity reactions constitute a global health problem, with an estimated incidence of 1 per 100,000 procedures and a mortality rate of 0.1 to 9 %. Main risk factors are a history of allergy to other drugs, atopy, associated psychiatric disorders and previous surgeri...

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Main Authors: Rodrigo Collado-Chagoya, Rubén Cruz-Pantoja, Javier Hernández-Romero, Cristóbal León-Oviedo, Rosa Isela Campos-Gutiérrez, Andrea Velasco-Medina, Guillermo Velázquez-Sámano
Format: Article
Language:English
Published: Colegio Mexicano de Inmunología Clínica y Alergia, A.C. 2018-10-01
Series:Revista Alergia México
Subjects:
Online Access:http://revistaalergia.mx/ojs/index.php/ram/article/view/513
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author Rodrigo Collado-Chagoya
Rubén Cruz-Pantoja
Javier Hernández-Romero
Cristóbal León-Oviedo
Rosa Isela Campos-Gutiérrez
Andrea Velasco-Medina
Guillermo Velázquez-Sámano
author_facet Rodrigo Collado-Chagoya
Rubén Cruz-Pantoja
Javier Hernández-Romero
Cristóbal León-Oviedo
Rosa Isela Campos-Gutiérrez
Andrea Velasco-Medina
Guillermo Velázquez-Sámano
author_sort Rodrigo Collado-Chagoya
collection DOAJ
description Background: Perioperative hypersensitivity reactions constitute a global health problem, with an estimated incidence of 1 per 100,000 procedures and a mortality rate of 0.1 to 9 %. Main risk factors are a history of allergy to other drugs, atopy, associated psychiatric disorders and previous surgeries. Objectives: To determine the frequency of sensitization and the type of drugs involved in perioperative allergy in a tertiary care hospital, over a 3-year period. Methods: Retrospective, cross-sectional, descriptive study of perioperative allergy, corroborated by skin tests for each drug and latex, of patients treated at the Allergy and Clinical Immunology Department of Hospital General de Mexico. Results: Twenty-eight patients diagnosed with perioperative allergy were included. Main triggers were neuromuscular blocking agents (46.42 %), latex (28.52 %) and propofol (14.28 %). The main risk factor was a history of previous surgeries (89.28 %). Most perioperative allergic reactions were mild (71.42 %) and occurred within the postoperative period (60.71 %). Conclusions: Initial diagnosis and Treatment should always be carried out by the anesthesiologist or surgeon, who should focus on the withdrawal of possible causative agents.
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spelling doaj.art-b27c9da2e2b0474c81f93bf12d8478682023-09-02T22:57:15ZengColegio Mexicano de Inmunología Clínica y Alergia, A.C.Revista Alergia México0002-51512448-91902018-10-0165437938810.29262/ram.v65i4.513380Perioperative allergy. A 3-year experienceRodrigo Collado-Chagoya0Rubén Cruz-Pantoja1Javier Hernández-Romero2Cristóbal León-Oviedo3Rosa Isela Campos-Gutiérrez4Andrea Velasco-Medina5Guillermo Velázquez-Sámano6Secretaría de Salud, Hospital General de México, Servicio Alergia e Inmunología Clínica, Ciudad de MéxicoSecretaría de Salud, Hospital General de México, Servicio Alergia e Inmunología Clínica, Ciudad de MéxicoSecretaría de Salud, Hospital General de México, Servicio Alergia e Inmunología Clínica, Ciudad de MéxicoSecretaría de Salud, Hospital General de México, Servicio Alergia e Inmunología Clínica, Ciudad de MéxicoSecretaría de Salud, Hospital General de México, Servicio Alergia e Inmunología Clínica, Ciudad de MéxicoSecretaría de Salud, Hospital General de México, Servicio Alergia e Inmunología Clínica, Ciudad de MéxicoSecretaría de Salud, Hospital General de México, Servicio Alergia e Inmunología Clínica, Ciudad de MéxicoBackground: Perioperative hypersensitivity reactions constitute a global health problem, with an estimated incidence of 1 per 100,000 procedures and a mortality rate of 0.1 to 9 %. Main risk factors are a history of allergy to other drugs, atopy, associated psychiatric disorders and previous surgeries. Objectives: To determine the frequency of sensitization and the type of drugs involved in perioperative allergy in a tertiary care hospital, over a 3-year period. Methods: Retrospective, cross-sectional, descriptive study of perioperative allergy, corroborated by skin tests for each drug and latex, of patients treated at the Allergy and Clinical Immunology Department of Hospital General de Mexico. Results: Twenty-eight patients diagnosed with perioperative allergy were included. Main triggers were neuromuscular blocking agents (46.42 %), latex (28.52 %) and propofol (14.28 %). The main risk factor was a history of previous surgeries (89.28 %). Most perioperative allergic reactions were mild (71.42 %) and occurred within the postoperative period (60.71 %). Conclusions: Initial diagnosis and Treatment should always be carried out by the anesthesiologist or surgeon, who should focus on the withdrawal of possible causative agents.http://revistaalergia.mx/ojs/index.php/ram/article/view/513alergia perioperatoriaanafilaxiabloqueadores neuromuscularesanestésicos localeshipnóticoslátex
spellingShingle Rodrigo Collado-Chagoya
Rubén Cruz-Pantoja
Javier Hernández-Romero
Cristóbal León-Oviedo
Rosa Isela Campos-Gutiérrez
Andrea Velasco-Medina
Guillermo Velázquez-Sámano
Perioperative allergy. A 3-year experience
Revista Alergia México
alergia perioperatoria
anafilaxia
bloqueadores neuromusculares
anestésicos locales
hipnóticos
látex
title Perioperative allergy. A 3-year experience
title_full Perioperative allergy. A 3-year experience
title_fullStr Perioperative allergy. A 3-year experience
title_full_unstemmed Perioperative allergy. A 3-year experience
title_short Perioperative allergy. A 3-year experience
title_sort perioperative allergy a 3 year experience
topic alergia perioperatoria
anafilaxia
bloqueadores neuromusculares
anestésicos locales
hipnóticos
látex
url http://revistaalergia.mx/ojs/index.php/ram/article/view/513
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