Adipose-Derived Mesenchymal Stem Cells Attenuate Immune Reactions Against Pig Decellularized Bronchi Engrafted into Rat Tracheal Defects

Adipose-Derived Mesenchymal Stem Cells Attenuate Immune Reactions Against Pig Decellularized Bronchi Engrafted into Rat Tracheal Defects

ABSTRACTDecellularized scaffolds are promising biomaterials for tissue and organ reconstruction; however, strategies to effectively suppress the host immune responses toward these implants, particularly those without chemical crosslinking, remain warranted. Administration of mesenchymal stem cells i...

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Bibliographic Details
Main Authors: Makoto Hisanaga, Tomoshi Tsuchiya, Hironosuke Watanabe, Koichiro Shimoyama, Mayumi Iwatake, Yukinori Tanoue, Keizaburo Maruyama, Hiroshi Yukawa, Kazuhide Sato, Yoshimi Kato, Keitaro Matsumoto, Takuro Miyazaki, Ryoichiro Doi, Koichi Tomoshige, Takeshi Nagayasu
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Organogenesis
Subjects:
Adipose-derived mesenchymal stem cells
biocompatible materials
decellularization
immunosuppression
tissue engineering
xenotransplantation
Online Access:https://www.tandfonline.com/doi/10.1080/15476278.2023.2212582

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