Contribution of <i>AGTR</i> 1 Promoter Region Polymorphism to the Progression and Outcome of Sepsis in Patients with Various Comorbidities

Contribution of <i>AGTR</i> 1 Promoter Region Polymorphism to the Progression and Outcome of Sepsis in Patients with Various Comorbidities

Blood pressure dysregulation and circulatory failure are major contributors to the progression of sepsis and especially septic shock. One of the genes affecting the vascular endothelium and arteriolar tone is the angiotensin II receptor 1 gene (AGTR1). The AGTR1 rs275651 single-nucleotide polymorphi...

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Bibliographic Details
Main Authors: A. G. Chumachenko, E. K. Grigoriev, V. M. Pisarev
Format: Article
Language:English
Published: Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia 2021-10-01
Series:Общая реаниматология
Subjects:
sepsis
septic shock
genetic polymorphism
agtr1
angiotensin ii receptor gene
diabetes mellitus
comorbidity
Online Access:https://www.reanimatology.com/rmt/article/view/2134

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