Selective electrical stimulation with current-field modulation

Selective electrical stimulation using a multielectrode array is a promising technique that can potentially bring electrical stimulation treatment modalities a step forward. A microcontroller-controlled electrical stimulator system delivering a single pulse was designed, suitable for current-field m...

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Main Authors: Kárason Halldór, Pilkington Óskar, Helgason Thordur
Format: Article
Language:English
Published: De Gruyter 2021-10-01
Series:Current Directions in Biomedical Engineering
Subjects:
Online Access:https://doi.org/10.1515/cdbme-2021-2205
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author Kárason Halldór
Pilkington Óskar
Helgason Thordur
author_facet Kárason Halldór
Pilkington Óskar
Helgason Thordur
author_sort Kárason Halldór
collection DOAJ
description Selective electrical stimulation using a multielectrode array is a promising technique that can potentially bring electrical stimulation treatment modalities a step forward. A microcontroller-controlled electrical stimulator system delivering a single pulse was designed, suitable for current-field modulation. The goal is to make electrical stimulation with surface electrodes more specific. A graphical user interface (GUI) was developed to control stimulation parameters and current-field within a multi-electrode array wirelessly. The stimulator generates arbitrary biphasic waveforms with a 5-bit resolution and high temporal precision (<10 μs) and was demonstrated to stimulate posterior lumbar root fibers in transcutaneous spinal cord stimulation (tSCS) treatment selectively. Current-field modulation throughout a sixteen-electrode array was achieved. The system has the goal to improve control of stimulation conditions in electrophysiological studies and time-dependent and site-specific stimulation patterns for neuromodulation applications. A novel feature is the current-field modulation ability of the stimulator for surface electrode arrays.
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spelling doaj.art-b281c4c2ca45473ba6c7143602fa58712022-12-22T04:35:04ZengDe GruyterCurrent Directions in Biomedical Engineering2364-55042021-10-017280380610.1515/cdbme-2021-2205Selective electrical stimulation with current-field modulationKárason Halldór0Pilkington Óskar1Helgason Thordur2Health Technology Center (Landspitali University Hospital, Reykjavík University),Reykjavík, IcelandThordur Helgason: Health Technology Center (Landspitali University Hospital, Reykjavík University),Reykjavík, IcelandHealth Technology Center (Landspitali University Hospital, Reykjavík University),Reykjavík, IcelandSelective electrical stimulation using a multielectrode array is a promising technique that can potentially bring electrical stimulation treatment modalities a step forward. A microcontroller-controlled electrical stimulator system delivering a single pulse was designed, suitable for current-field modulation. The goal is to make electrical stimulation with surface electrodes more specific. A graphical user interface (GUI) was developed to control stimulation parameters and current-field within a multi-electrode array wirelessly. The stimulator generates arbitrary biphasic waveforms with a 5-bit resolution and high temporal precision (<10 μs) and was demonstrated to stimulate posterior lumbar root fibers in transcutaneous spinal cord stimulation (tSCS) treatment selectively. Current-field modulation throughout a sixteen-electrode array was achieved. The system has the goal to improve control of stimulation conditions in electrophysiological studies and time-dependent and site-specific stimulation patterns for neuromodulation applications. A novel feature is the current-field modulation ability of the stimulator for surface electrode arrays.https://doi.org/10.1515/cdbme-2021-2205electrical stimulationmicrocontrollertranscutaneousmulti-electrode arrayspinal cordfocused stimulation
spellingShingle Kárason Halldór
Pilkington Óskar
Helgason Thordur
Selective electrical stimulation with current-field modulation
Current Directions in Biomedical Engineering
electrical stimulation
microcontroller
transcutaneous
multi-electrode array
spinal cord
focused stimulation
title Selective electrical stimulation with current-field modulation
title_full Selective electrical stimulation with current-field modulation
title_fullStr Selective electrical stimulation with current-field modulation
title_full_unstemmed Selective electrical stimulation with current-field modulation
title_short Selective electrical stimulation with current-field modulation
title_sort selective electrical stimulation with current field modulation
topic electrical stimulation
microcontroller
transcutaneous
multi-electrode array
spinal cord
focused stimulation
url https://doi.org/10.1515/cdbme-2021-2205
work_keys_str_mv AT karasonhalldor selectiveelectricalstimulationwithcurrentfieldmodulation
AT pilkingtonoskar selectiveelectricalstimulationwithcurrentfieldmodulation
AT helgasonthordur selectiveelectricalstimulationwithcurrentfieldmodulation