Rac1 activation can generate untemplated, lamellar membrane ruffles

Rac1 activation can generate untemplated, lamellar membrane ruffles

Abstract Background Membrane protrusions that occur on the dorsal surface of a cell are an excellent experimental system to study actin machinery at work in a living cell. Small GTPase Rac1 controls the membrane protrusions that form and encapsulate extracellular volumes to perform pinocytic or phag...

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Bibliographic Details
Main Authors: F. Leyden, S. Uthishtran, U. K. Moorthi, H. M. York, A. Patil, H. Gandhi, E. P. Petrov, T. Bornschlögl, S. Arumugam
Format: Article
Language:English
Published: BMC 2021-04-01
Series:BMC Biology
Subjects:
Lattice light-sheet microscopy
Optogenetics
Actin polymerization
Lamellipodia
Rac1
Online Access:https://doi.org/10.1186/s12915-021-00997-3

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