Homeostase glicêmica e marcadores antropométricos associados à resistência insulínica em pacientes portadores de doença hepática gordurosa não alcoólica
Objective: To determine predictive anthropometric measurements associated with insulin resistance in patients with non-alcoholic fatty liver disease. Methods: This was a cross-sectional, quantitative study conducted at two outpatient clinics in Recife-PE. The study group was formed by individuals of...
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| Format: | Article |
| Language: | English |
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Universidade do Estado do Rio de Janeiro
2021-03-01
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| Series: | Demetra |
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| Online Access: | https://www.e-publicacoes.uerj.br/index.php/demetra/article/view/45633 |
| _version_ | 1811306148453679104 |
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| author | Emerson Iago Garcia e Silva Sarah Emanuely Macêdo Gudes Bárbara Evelin de Souza Cunha Camilla Araújo de Brito |
| author_facet | Emerson Iago Garcia e Silva Sarah Emanuely Macêdo Gudes Bárbara Evelin de Souza Cunha Camilla Araújo de Brito |
| author_sort | Emerson Iago Garcia e Silva |
| collection | DOAJ |
| description | Objective: To determine predictive anthropometric measurements associated with insulin resistance in patients with non-alcoholic fatty liver disease. Methods: This was a cross-sectional, quantitative study conducted at two outpatient clinics in Recife-PE. The study group was formed by individuals of both sexes over 18 years of age with non-alcoholic fatty liver disease diagnosed via abdominal echography. The anthropometric variables collected were: waist circumference, body mass index, conicity index, waist-to-hip ratio, and waist-to-height ratio. Insulin resistance was determined through the homeostasis model assessment: insulin resistance (HOMA-IR). The Mann–Whitney U test and correlation tests were performed to understand the differences between the variables. Results: 75 individuals participated in the study, most of whom were female (85%) and with age over 60 years (44%). Insulin resistance was high in the population, being present in more than half of the individuals (73%). Except for the body mass index and waist-to-hip ratio, all other indices showed a significant association between the presence of insulin resistance and non-alcoholic hepatic steatosis: waist-to-height ratio (p= 0.004), conicity index (p= 0.031), and waist circumference (p= 0.001). In the correlation test, only the waist circumference (r= 0.2184; p= 0.05) and the waist-to-hip ratio (r = 0.2310; p= 0.04) were associated. Conclusions: The anthropometric indicators are applicable tools in clinical practice and in the context of non-alcoholic fatty liver disease; however, waist circumference and the waist-to-height and waist-to-hip ratios provided the best predictions. |
| first_indexed | 2024-04-13T08:39:13Z |
| format | Article |
| id | doaj.art-b28b596f579947a7bd470fd8d1c5fcba |
| institution | Directory Open Access Journal |
| issn | 2238-913X |
| language | English |
| last_indexed | 2024-04-13T08:39:13Z |
| publishDate | 2021-03-01 |
| publisher | Universidade do Estado do Rio de Janeiro |
| record_format | Article |
| series | Demetra |
| spelling | doaj.art-b28b596f579947a7bd470fd8d1c5fcba2022-12-22T02:53:58ZengUniversidade do Estado do Rio de JaneiroDemetra2238-913X2021-03-01160e45633e4563310.12957/demetra.2021.4563328795Homeostase glicêmica e marcadores antropométricos associados à resistência insulínica em pacientes portadores de doença hepática gordurosa não alcoólicaEmerson Iago Garcia e Silva0Sarah Emanuely Macêdo GudesBárbara Evelin de Souza CunhaCamilla Araújo de BritoUniversidade de Pernambuco/ Programa de Pós-graduação em Ciência e Tecnologia Ambiental para o SemiáridoObjective: To determine predictive anthropometric measurements associated with insulin resistance in patients with non-alcoholic fatty liver disease. Methods: This was a cross-sectional, quantitative study conducted at two outpatient clinics in Recife-PE. The study group was formed by individuals of both sexes over 18 years of age with non-alcoholic fatty liver disease diagnosed via abdominal echography. The anthropometric variables collected were: waist circumference, body mass index, conicity index, waist-to-hip ratio, and waist-to-height ratio. Insulin resistance was determined through the homeostasis model assessment: insulin resistance (HOMA-IR). The Mann–Whitney U test and correlation tests were performed to understand the differences between the variables. Results: 75 individuals participated in the study, most of whom were female (85%) and with age over 60 years (44%). Insulin resistance was high in the population, being present in more than half of the individuals (73%). Except for the body mass index and waist-to-hip ratio, all other indices showed a significant association between the presence of insulin resistance and non-alcoholic hepatic steatosis: waist-to-height ratio (p= 0.004), conicity index (p= 0.031), and waist circumference (p= 0.001). In the correlation test, only the waist circumference (r= 0.2184; p= 0.05) and the waist-to-hip ratio (r = 0.2310; p= 0.04) were associated. Conclusions: The anthropometric indicators are applicable tools in clinical practice and in the context of non-alcoholic fatty liver disease; however, waist circumference and the waist-to-height and waist-to-hip ratios provided the best predictions.https://www.e-publicacoes.uerj.br/index.php/demetra/article/view/45633antropometria. doenças crônicas não transmissíveis. resistência à insulina. esteatose hepática. |
| spellingShingle | Emerson Iago Garcia e Silva Sarah Emanuely Macêdo Gudes Bárbara Evelin de Souza Cunha Camilla Araújo de Brito Homeostase glicêmica e marcadores antropométricos associados à resistência insulínica em pacientes portadores de doença hepática gordurosa não alcoólica Demetra antropometria. doenças crônicas não transmissíveis. resistência à insulina. esteatose hepática. |
| title | Homeostase glicêmica e marcadores antropométricos associados à resistência insulínica em pacientes portadores de doença hepática gordurosa não alcoólica |
| title_full | Homeostase glicêmica e marcadores antropométricos associados à resistência insulínica em pacientes portadores de doença hepática gordurosa não alcoólica |
| title_fullStr | Homeostase glicêmica e marcadores antropométricos associados à resistência insulínica em pacientes portadores de doença hepática gordurosa não alcoólica |
| title_full_unstemmed | Homeostase glicêmica e marcadores antropométricos associados à resistência insulínica em pacientes portadores de doença hepática gordurosa não alcoólica |
| title_short | Homeostase glicêmica e marcadores antropométricos associados à resistência insulínica em pacientes portadores de doença hepática gordurosa não alcoólica |
| title_sort | homeostase glicemica e marcadores antropometricos associados a resistencia insulinica em pacientes portadores de doenca hepatica gordurosa nao alcoolica |
| topic | antropometria. doenças crônicas não transmissíveis. resistência à insulina. esteatose hepática. |
| url | https://www.e-publicacoes.uerj.br/index.php/demetra/article/view/45633 |
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