Identification of key modules in metabolic syndrome induced by second-generation antipsychotics based on co-expression network analysis

Identification of key modules in metabolic syndrome induced by second-generation antipsychotics based on co-expression network analysis

Background: Second-generation antipsychotics (SGAs) frequently cause metabolic syndrome (MetS), which raises the risk of heart disease, type 2 diabetes, morbid obesity, atherosclerosis, and hypertension. MetS also impairs cognitive function in patients with schizophrenia. However, the fundamental re...

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Bibliographic Details
Main Authors: Ying Sun, Cuizhen Zhu, Lixuan Huang, Chao Luo, Peijun Ju, Jianhua Chen
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Schizophrenia
Metabolic syndrome
Second-generation antipsychotic
RNA sequencing
WGCNA
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037024000035

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