Advanced paternal age: effects on sperm parameters, assisted reproduction outcomes and offspring health
Abstract Many factors, including postponement of marriage, increased life expectancy, and improved success with assisted reproductive technologies have been contributing to increased paternal age in developed nations. This increased average paternal age has led to concerns about adverse effects of a...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2020-11-01
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| Series: | Reproductive Biology and Endocrinology |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12958-020-00668-y |
| _version_ | 1819172957978624000 |
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| author | Iman Halvaei Julia Litzky Navid Esfandiari |
| author_facet | Iman Halvaei Julia Litzky Navid Esfandiari |
| author_sort | Iman Halvaei |
| collection | DOAJ |
| description | Abstract Many factors, including postponement of marriage, increased life expectancy, and improved success with assisted reproductive technologies have been contributing to increased paternal age in developed nations. This increased average paternal age has led to concerns about adverse effects of advanced paternal age on sperm quality, assisted reproductive outcomes, and the health of the offspring conceived by older fathers. This review discusses the association between advanced paternal age and sperm parameters, assisted reproduction success rates, and offspring health. |
| first_indexed | 2024-12-22T20:15:27Z |
| format | Article |
| id | doaj.art-b28e2cf1d571474f84df54f1c86236c9 |
| institution | Directory Open Access Journal |
| issn | 1477-7827 |
| language | English |
| last_indexed | 2024-12-22T20:15:27Z |
| publishDate | 2020-11-01 |
| publisher | BMC |
| record_format | Article |
| series | Reproductive Biology and Endocrinology |
| spelling | doaj.art-b28e2cf1d571474f84df54f1c86236c92022-12-21T18:13:59ZengBMCReproductive Biology and Endocrinology1477-78272020-11-0118111210.1186/s12958-020-00668-yAdvanced paternal age: effects on sperm parameters, assisted reproduction outcomes and offspring healthIman Halvaei0Julia Litzky1Navid Esfandiari2Department of Anatomical Sciences, Faculty of Medical Sciences, Tarbiat Modares UniversityDepartment of Pediatrics, Dartmouth Hitchcock Medical CenterDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of Vermont Medical Center, Larner College of MedicineAbstract Many factors, including postponement of marriage, increased life expectancy, and improved success with assisted reproductive technologies have been contributing to increased paternal age in developed nations. This increased average paternal age has led to concerns about adverse effects of advanced paternal age on sperm quality, assisted reproductive outcomes, and the health of the offspring conceived by older fathers. This review discusses the association between advanced paternal age and sperm parameters, assisted reproduction success rates, and offspring health.http://link.springer.com/article/10.1186/s12958-020-00668-yMale ageAgingPregnancyLive birthSperm |
| spellingShingle | Iman Halvaei Julia Litzky Navid Esfandiari Advanced paternal age: effects on sperm parameters, assisted reproduction outcomes and offspring health Reproductive Biology and Endocrinology Male age Aging Pregnancy Live birth Sperm |
| title | Advanced paternal age: effects on sperm parameters, assisted reproduction outcomes and offspring health |
| title_full | Advanced paternal age: effects on sperm parameters, assisted reproduction outcomes and offspring health |
| title_fullStr | Advanced paternal age: effects on sperm parameters, assisted reproduction outcomes and offspring health |
| title_full_unstemmed | Advanced paternal age: effects on sperm parameters, assisted reproduction outcomes and offspring health |
| title_short | Advanced paternal age: effects on sperm parameters, assisted reproduction outcomes and offspring health |
| title_sort | advanced paternal age effects on sperm parameters assisted reproduction outcomes and offspring health |
| topic | Male age Aging Pregnancy Live birth Sperm |
| url | http://link.springer.com/article/10.1186/s12958-020-00668-y |
| work_keys_str_mv | AT imanhalvaei advancedpaternalageeffectsonspermparametersassistedreproductionoutcomesandoffspringhealth AT julialitzky advancedpaternalageeffectsonspermparametersassistedreproductionoutcomesandoffspringhealth AT navidesfandiari advancedpaternalageeffectsonspermparametersassistedreproductionoutcomesandoffspringhealth |