Determination of thimerosal in non-adsorbed immunobiological preparations by cold vapor atomic absorption spectroscopy (CV AAS) for the ions of mercury. Part 1: method development and evaluation of statistical significance of differences in the results of mercury ions determination by colorimetric method and cold vapor atomic absorption spectroscopy method
The article describes development of methods of quantitative determination of thimerosal in non-adsorbed immunobiological preparations by cold vapor atomic absorption spectroscopy as well as an estimation of the statistical significance of differences in the results determination of thimerosal conve...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
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Ministry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products»
2018-02-01
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| Series: | Биопрепараты: Профилактика, диагностика, лечение |
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| Online Access: | https://www.biopreparations.ru/jour/article/view/15 |
| _version_ | 1797244586576314368 |
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| author | O. N. Kolesnikova O. B. Ustinnikova O. B. Runova V. P. Bondarev |
| author_facet | O. N. Kolesnikova O. B. Ustinnikova O. B. Runova V. P. Bondarev |
| author_sort | O. N. Kolesnikova |
| collection | DOAJ |
| description | The article describes development of methods of quantitative determination of thimerosal in non-adsorbed immunobiological preparations by cold vapor atomic absorption spectroscopy as well as an estimation of the statistical significance of differences in the results determination of thimerosal conventional colorimetric method in combination with dithizone and CV AAS using one-way analysis of variance with Fisher’s exact test (F-test). |
| first_indexed | 2024-03-08T21:44:21Z |
| format | Article |
| id | doaj.art-b28e600b615e485696675916072b3bdc |
| institution | Directory Open Access Journal |
| issn | 2221-996X 2619-1156 |
| language | Russian |
| last_indexed | 2024-04-24T19:13:22Z |
| publishDate | 2018-02-01 |
| publisher | Ministry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» |
| record_format | Article |
| series | Биопрепараты: Профилактика, диагностика, лечение |
| spelling | doaj.art-b28e600b615e485696675916072b3bdc2024-03-26T09:10:51ZrusMinistry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products»Биопрепараты: Профилактика, диагностика, лечение2221-996X2619-11562018-02-0102596315Determination of thimerosal in non-adsorbed immunobiological preparations by cold vapor atomic absorption spectroscopy (CV AAS) for the ions of mercury. Part 1: method development and evaluation of statistical significance of differences in the results of mercury ions determination by colorimetric method and cold vapor atomic absorption spectroscopy methodO. N. Kolesnikova0O. B. Ustinnikova1O. B. Runova2V. P. Bondarev3Federal State Budgetary Institution «Scientific Center on Expertise of Medical Application Products» Ministry of Health of the Russian FederationFederal State Budgetary Institution «Scientific Center on Expertise of Medical Application Products» Ministry of Health of the Russian FederationFederal State Budgetary Institution «Scientific Center on Expertise of Medical Application Products» Ministry of Health of the Russian FederationFederal State Budgetary Institution «Scientific Center on Expertise of Medical Application Products» Ministry of Health of the Russian FederationThe article describes development of methods of quantitative determination of thimerosal in non-adsorbed immunobiological preparations by cold vapor atomic absorption spectroscopy as well as an estimation of the statistical significance of differences in the results determination of thimerosal conventional colorimetric method in combination with dithizone and CV AAS using one-way analysis of variance with Fisher’s exact test (F-test).https://www.biopreparations.ru/jour/article/view/15thimerosalquantitative evaluationassessment atomic absorption spectroscopystatistical significance of differencesмертиолятколичественная оценкаатомно-абсобционная спектроскопия холодного парастатистически значимые различия |
| spellingShingle | O. N. Kolesnikova O. B. Ustinnikova O. B. Runova V. P. Bondarev Determination of thimerosal in non-adsorbed immunobiological preparations by cold vapor atomic absorption spectroscopy (CV AAS) for the ions of mercury. Part 1: method development and evaluation of statistical significance of differences in the results of mercury ions determination by colorimetric method and cold vapor atomic absorption spectroscopy method Биопрепараты: Профилактика, диагностика, лечение thimerosal quantitative evaluation assessment atomic absorption spectroscopy statistical significance of differences мертиолят количественная оценка атомно-абсобционная спектроскопия холодного пара статистически значимые различия |
| title | Determination of thimerosal in non-adsorbed immunobiological preparations by cold vapor atomic absorption spectroscopy (CV AAS) for the ions of mercury. Part 1: method development and evaluation of statistical significance of differences in the results of mercury ions determination by colorimetric method and cold vapor atomic absorption spectroscopy method |
| title_full | Determination of thimerosal in non-adsorbed immunobiological preparations by cold vapor atomic absorption spectroscopy (CV AAS) for the ions of mercury. Part 1: method development and evaluation of statistical significance of differences in the results of mercury ions determination by colorimetric method and cold vapor atomic absorption spectroscopy method |
| title_fullStr | Determination of thimerosal in non-adsorbed immunobiological preparations by cold vapor atomic absorption spectroscopy (CV AAS) for the ions of mercury. Part 1: method development and evaluation of statistical significance of differences in the results of mercury ions determination by colorimetric method and cold vapor atomic absorption spectroscopy method |
| title_full_unstemmed | Determination of thimerosal in non-adsorbed immunobiological preparations by cold vapor atomic absorption spectroscopy (CV AAS) for the ions of mercury. Part 1: method development and evaluation of statistical significance of differences in the results of mercury ions determination by colorimetric method and cold vapor atomic absorption spectroscopy method |
| title_short | Determination of thimerosal in non-adsorbed immunobiological preparations by cold vapor atomic absorption spectroscopy (CV AAS) for the ions of mercury. Part 1: method development and evaluation of statistical significance of differences in the results of mercury ions determination by colorimetric method and cold vapor atomic absorption spectroscopy method |
| title_sort | determination of thimerosal in non adsorbed immunobiological preparations by cold vapor atomic absorption spectroscopy cv aas for the ions of mercury part 1 method development and evaluation of statistical significance of differences in the results of mercury ions determination by colorimetric method and cold vapor atomic absorption spectroscopy method |
| topic | thimerosal quantitative evaluation assessment atomic absorption spectroscopy statistical significance of differences мертиолят количественная оценка атомно-абсобционная спектроскопия холодного пара статистически значимые различия |
| url | https://www.biopreparations.ru/jour/article/view/15 |
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