Effect of Methimasole Therapy on Thyroid Patohistology that may Mimic Thyroid Malignancy
Diffuse toxic goiter, as the most common cause of hyperthyroidism, is usually initially treated with thyrostatic drugs such as methimazole, followed by radioiodine therapy or surgery which may be indicated as definitive treatment. Radioactive iodine therapy has a known association with various hi...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Sestre Milosrdnice University hospital, Institute of Clinical Medical Research
2020-01-01
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| Series: | Acta Clinica Croatica |
| Subjects: | |
| Online Access: | https://hrcak.srce.hr/file/361405 |
| Summary: | Diffuse toxic goiter, as the most common cause of hyperthyroidism, is usually
initially treated with thyrostatic drugs such as methimazole, followed by radioiodine therapy or surgery
which may be indicated as definitive treatment. Radioactive iodine therapy has a known association
with various histopathologic features including cytologic atypia, but herein we present a rare example
of morphological thyrocyte changes induced by long-term pharmacological treatment with
methimazole that mimicked thyroid malignancy in a pathohistological sample. |
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| ISSN: | 0353-9466 1333-9451 |